NOAEL Data Cosmetic Ingredient

Caffeic acid phenethyl ester

Also known as: CAPE, 2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester, 2-Phenylethyl 3-(3,4-dihydroxyphenyl)acrylate, 2-Phenylethyl caffeate, β-Phenylethyl caffeate (+3 more)

CAS 104594-70-9

Caffeic acid phenethyl ester (CAS 104594-70-9) is a chemical substance. Key regulatory status: cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.

View cosmetic safety profile for Phenethyl Caffeate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
0
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields
Name
Caffeic acid phenethyl ester
CAS Number
104594-70-9
DTXSID
DTXSID8040987
Molecular Formula
C17H16O4
InChI Key
SWUARLUWKZWEBQ-UHFFFAOYSA-N
Monoisotopic Mass
284.104859
Synonyms
CAPE2-Propenoic acid, 3-(3,4-dihydroxyphenyl)-, 2-phenylethyl ester2-Phenylethyl 3-(3,4-dihydroxyphenyl)acrylate2-Phenylethyl caffeateβ-Phenylethyl caffeate2-phenylethyl 3-(3,4-dihydroxyphenyl)-2-propenoateUNII-G960R9S5SKPhenethyl caffeate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records
Antioxidant

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
G960R9S5SKUNIIFDA UNII substance identifier--openFDA substances
G960R9S5SKUNIIFDA UNII substance identifier--openFDA substances
G960R9S5SKUNIIFDA UNII substance identifier--openFDA substances
G960R9S5SKUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Antioxidant
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CAFFEIC ACID PHENETHYL ESTER
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
8
View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Caffeic acid phenethyl ester?

Caffeic acid phenethyl ester has 4 NOAEL studies in the database. The lowest reported value is G960R9S5SK UNII. Source: openFDA substances.

Is Caffeic acid phenethyl ester used in cosmetics?

Yes, Caffeic acid phenethyl ester is also indexed as a cosmetic ingredient under the name Phenethyl Caffeate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Caffeic acid phenethyl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Caffeic acid phenethyl ester used outside industrial chemicals?

Caffeic acid phenethyl ester also appears in cosmetics, pharmaceutical databases.