What is the NOAEL for (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid?
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid has 4 NOAEL studies in the database. The lowest reported value is AAN7QOV9EA UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid
Also known as: 5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)-, (all-cis)-5,8,11,14,17-Eicosapentaenoic acid, (all-Z)-5,8,11,14,17-Eicosapentaenoic acid, (all-Z)-Δ5,8,11,14,17-Eicosapentaenoic acid, 5,8,11,14,17-Eicosapentaenoic acid (+14 more)
CAS 10417-94-4
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid (CAS 10417-94-4) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
Cross-Vertical Regulatory Divergence
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid is classified GHS Danger (H314) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
25 fields
Name
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid
CAS Number
10417-94-4
DTXSID
DTXSID9041023
Molecular Formula
C20H30O2
InChI Key
JAZBEHYOTPTENJ-JLNKQSITSA-N
Monoisotopic Mass
302.22458
Synonyms
5,8,11,14,17-Eicosapentaenoic acid, (5Z,8Z,11Z,14Z,17Z)-(all-cis)-5,8,11,14,17-Eicosapentaenoic acid(all-Z)-5,8,11,14,17-Eicosapentaenoic acid(all-Z)-Δ5,8,11,14,17-Eicosapentaenoic acid5,8,11,14,17-Eicosapentaenoic acid5,8,11,14,17-Eicosapentaenoic acid, (all-Z)-IcosapentIcosapentaenoic acidIncromega E 7010SR(5Z,8Z,11Z,14Z,17Z)-Eicosa-5,8,11,14,17-pentaenoic acidEPA(all-Z)-delta5,8,11,14,17-Eicosapentaenoic acid
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| AAN7QOV9EA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AAN7QOV9EA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AAN7QOV9EA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| AAN7QOV9EA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fatty Acids
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ICOSAPENT
ChEMBL Phase
3
Adverse Events
1992
Bioactivity
15
Frequently Asked Questions
What regulatory lists include (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid?
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid appears on 4 regulatory/inventory lists including Canada; consumer_product; Substances in Products - Canada (4/2014), Canada; Personal care; Substances in PCP - Canada (4/2014), pharmaceutical, and 1 more. Source: EPA CPDat.
Is (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid used in cosmetics?
Yes, (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid is also indexed as a cosmetic ingredient under the name Eicosapentaenoic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid have different safety status in cosmetics vs industrial chemicals?
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid is classified GHS Danger (H314) in the chemicals database but is allowed in EU cosmetics.
Is (5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid used outside industrial chemicals?
(5Z,8Z,11Z,14Z,17Z)-Eicosapentaenoic acid also appears in cosmetics, pharmaceutical databases.