EFSA toxicology reference values
2,3-Diethylpyrazine
2,3-Diethylpyrazine (CAS 15707-24-1). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
2,3-Diethylpyrazine is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
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EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MSI/FC | 0.3 mg/kg | other: | - | - |
| MSI/FC | 0.3 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | other: | - | - |
| MSI/FC | 0.5 mg/kg | salmon | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| TTC Cramer Class II | 9 µg/kg bw/day | consumers | - | - |
| PNEC | 46 µg/L | other: | 09f9ddd7-0d49-4656-9f73-6b6cc99f3351 | - |
| PNEC | 236 µg/kg | other: | 40c1409a-1d65-4f70-92d8-dbd9edda0a72 | - |
| margin of safety | - | consumers | - | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| toxicity to soil arthropods: short-term | other: | - | - | - |
| toxicity to aquatic algae and cyanobacteria | other: | - | - | - |
| Carcinogenicity_EU_PPP | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present consideration concerns 41 pyrazine derivatives evaluated by the JECFA (57th meeting) and will be considered in relation to the EFSA evaluation of 21 pyrazine derivatives evaluated in the Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2). The Panel concluded that the 41 substances in the JECFA flavouring group of pyrazines are structurally related to the pyrazines evaluated by EFSA in FGE.17Rev2. |
| Carcinogenicity_EU_PPP | - | - | - | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 22 compounds belonging to chemical group 24 (pyrazine derivatives). |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns 41 pyrazine derivatives evaluated by the JECFA (57th meeting) and will be considered in relation to the EFSA evaluation of 18 pyrazine derivatives evaluated in the Flavouring Group Evaluation 17 (FGE.17). |
| Genetic Toxicity | - | - | - | Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of 22 compounds belonging to chemical group 24 (pyrazine derivatives). |
| Genetic Toxicity | - | - | - | The European Food Safety Authority (EFSA) asked the Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC and its consecutive amendments. The present consideration concerns 41 pyrazine derivatives evaluated by the JECFA (57th meeting) and will be considered in relation to the EFSA evaluation of 21 pyrazine derivatives evaluated in the Flavouring Group Evaluation 17, Revision 2 (FGE.17Rev2). The Panel concluded that the 41 substances in the JECFA flavouring group of pyrazines are structurally related to the pyrazines evaluated by EFSA in FGE.17Rev2. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. The present consideration concerns 41 pyrazine derivatives evaluated by the JECFA (57th meeting) and will be considered in relation to the EFSA evaluation of 18 pyrazine derivatives evaluated in the Flavouring Group Evaluation 17 (FGE.17). |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for 2,3-Diethylpyrazine in cannabis?
2,3-Diethylpyrazine does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 2,3-Diethylpyrazine?
2,3-Diethylpyrazine does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 2,3-Diethylpyrazine?
2,3-Diethylpyrazine has 10 EFSA OpenFoodTox reference value rows in the cannabis database, including MSI/FC, TTC Cramer Class II, PNEC, margin of safety.
Is 2,3-Diethylpyrazine also regulated in cosmetics or food?
2,3-Diethylpyrazine has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.