EFSA toxicology reference values
4-Hexylresorcinol
4-Hexylresorcinol (CAS 136-77-6). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
4-Hexylresorcinol is a cannabis analyte contaminant represented in the cannabis public dataset.
Substance Identity
Analyte identity and classification used for this cannabis substance page.
Contaminant Class Badge
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Dataset Snapshot
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EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| margin of safety | 1,200 other: | adults | 7a345a0f-64d8-4535-b0a8-7bbe46e03f48 | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| sub-chronic toxicity: other route | mouse | - | 4 mg/kg bw/day | - |
| Carcinogenicity_EU_PPP | - | - | - | The Panel ANS delivers an opinion re-evaluating the safety of an antioxidant 4-hexylresorcinol (4-HR)(E 586). The SCF in 2003 and the JECFA in 1996 recognised that available database was not sufficient to establish an ADI but considered 4-HR toxicologically acceptable for prevention of melanosis in shrimps provided residues in crustacean meat did not exceed 2 mg/kg (SCF) or 1 mg/kg (JECFA). The Panel was not provided with a newly submitted dossier and no new toxicological or biological information was submitted for the present re-evaluation. The Panel agreed with the SCF that the database did not allow the establishment of an ADI. The Panel considered nephropathy in mice as the most sensitive endpoint for 4-HR toxicity. The Panel concluded that any increase in the permitted use would require additional reproductive toxicity studies. |
| Genetic Toxicity | - | - | - | The Panel ANS delivers an opinion re-evaluating the safety of an antioxidant 4-hexylresorcinol (4-HR)(E 586). The SCF in 2003 and the JECFA in 1996 recognised that available database was not sufficient to establish an ADI but considered 4-HR toxicologically acceptable for prevention of melanosis in shrimps provided residues in crustacean meat did not exceed 2 mg/kg (SCF) or 1 mg/kg (JECFA). The Panel was not provided with a newly submitted dossier and no new toxicological or biological information was submitted for the present re-evaluation. The Panel agreed with the SCF that the database did not allow the establishment of an ADI. The Panel considered nephropathy in mice as the most sensitive endpoint for 4-HR toxicity. The Panel concluded that any increase in the permitted use would require additional reproductive toxicity studies. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
What is the regulatory limit for 4-Hexylresorcinol in cannabis?
4-Hexylresorcinol does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 4-Hexylresorcinol?
4-Hexylresorcinol does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 4-Hexylresorcinol?
4-Hexylresorcinol has 1 EFSA OpenFoodTox reference value row in the cannabis database, including margin of safety.
Is 4-Hexylresorcinol also regulated in cosmetics or food?
4-Hexylresorcinol has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.