EFSA toxicology reference values
3,4-Dihydrocoumarin
SOURCE
EFSA
3,4-Dihydrocoumarin (CAS 119-84-6). Cannabis testing data across 0 states. Action levels when present, testing requirements, compliance status.
3,4-Dihydrocoumarin is a cannabis analyte contaminant represented in the cannabis public dataset.
CAS 119-84-6
Cannabis Analyte
Substance Identity
Analyte identity and classification used for this cannabis substance page.
SOURCE
EFSA
Analyte name
3,4-Dihydrocoumarin
CAS number
119-84-6
Contaminant class
Cannabis Analyte
Contaminant Class Badge
Color-coded cannabis class signal for scanning pesticide, metal, solvent, mycotoxin, and potency pages.
SOURCE
State Cannabis Regulations
Cannabis Analyte
Cannabis contaminant class used to group state testing rows.
Dataset Snapshot
Compact public-data summary for page quality, state coverage, lab rows, and potency sample groups.
SOURCE
cannabis page data
Quality score
2
thin
Jurisdictions
0
No state rows
Lab/analyte rows
0
0 failed (-)
Potency samples
0
119-84-6
EFSA Substance Identity
EFSA substance identity rows matched by chemical name or CAS.
SOURCE
EFSA
3,4-Dihydrocoumarin
CAS 119-84-6 / mono-constituent substance
C9H8O2 / 3 dossier(s)
EFSA Reference Values
Reference values from efsa_reference_values_v2 for toxicology and food-safety context.
SOURCE
EFSA
| Descriptor | Value | Population | Endpoint | Body |
|---|---|---|---|---|
| MSI/FC | 1.5 mg/kg bw/day | cattle for fattening | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| MSI/FC | 1.5 mg/kg bw/day | cat | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| TTC Cramer Class III | 1.5 µg/kg bw/day | consumers | - | - |
| MSI/FC | 1.5 mg/kg bw/day | cattle for fattening | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | laying hen | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | dog | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | other: | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | chicken for fattening | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | dairy cow | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | turkey for fattening | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
| MSI/FC | 1.5 mg/kg bw/day | other: | 877bec67-0124-4659-bc33-4e27eb14ed80 | - |
EFSA Study Results
Endpoint-level study rows from efsa_study_results matched to this substance.
SOURCE
EFSA
| Endpoint | Species | Route | Effect | Assessment |
|---|---|---|---|---|
| sub-chronic toxicity: other route | rat | - | 150 mg/kg bw/day | - |
| sub-chronic toxicity: other route | rat | - | 150 mg/kg bw/day | - |
| sub-chronic toxicity: other route | rat | - | 150 mg/kg bw/day | - |
| chronic toxicity: oral | rat | oral: gavage | 300 other: | - |
| chronic toxicity: oral | rat | oral: gavage | 300 other: | - |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns a group of 16 alicyclic, alicyclic-fused and aromatic- fused ring lactones evaluated by the JECFA at their 61st meeting. One of the JECFA evaluated substances is not in the Register (dihydro-5-((Z,Z)octa-2,5-dienyl)-2(3H)-furanone) (JECFA-no: 1160) and four [FL-no: 10.034, 10.036, 10.169, 13.012] are precursors for alpha,beta-unsaturated ketones and will be considered together with other alpha,beta-unsaturated ketones and aldehydes. The Panel concluded that the remaining 11 substances in the JECFA flavouring group of alicyclic, alicyclic fused and aromatic-fused ring lactones are structurally related to the aromatic lactone in the FGE.27, as well as to a group of lactones in FGE.10 and the hydrolysis products to secondary and tertiary alcohols in FGE.09 and FGE.18, respectively. |
| Carcinogenicity_EU_PPP | - | - | - | EFSA shall deliver an opinion on the safety for the target animals, consumer, user and the environment and the efficacy of the active substances 3-propylidenephthalide, 3-butylidenephthalide and 3,4-dihydrocoumarin. |
| Carcinogenicity_EU_PPP | - | - | - | The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The present consideration concerns 13 alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by the JECFA (61st meeting) and will be considered in relation to the European Food Safety in the Flavouring Group Evaluation 27 (FGE.27). Furthermore, the JECFA evaluation is supported by a group of lactones evaluated in FGE.10 as well as by alicyclic secondary and tertiary alcohols in FGE.09 and FGE.18, respectively. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Food Contact Materials, Enzymes, Flavourings and Processing Aids (the Panel) was asked to provide scientific advice to the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular, the Panel was requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217 EC and its consecutive amendments. The present consideration concerns 13 alicyclic, alicyclic-fused and aromatic-fused ring lactones evaluated by the JECFA (61st meeting) and will be considered in relation to the European Food Safety in the Flavouring Group Evaluation 27 (FGE.27). Furthermore, the JECFA evaluation is supported by a group of lactones evaluated in FGE.10 as well as by alicyclic secondary and tertiary alcohols in FGE.09 and FGE.18, respectively. |
| Genetic Toxicity | - | - | - | The Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (the Panel) is asked to advise the Commission on the implications for human health of chemically defined flavouring substances used in or on foodstuffs in the Member States. In particular the Scientific Panel is requested to consider the Joint FAO/WHO Expert Committee on Food Additives (the JECFA) evaluations of flavouring substances assessed since 2000, and to decide whether no further evaluation is necessary, as laid down in Commission Regulation (EC) No 1565/2000. These flavouring substances are listed in the Register, which was adopted by Commission Decision 1999/217/EC, and its consecutive amendments. The present consideration concerns a group of 16 alicyclic, alicyclic-fused and aromatic- fused ring lactones evaluated by the JECFA at their 61st meeting. One of the JECFA evaluated substances is not in the Register (dihydro-5-((Z,Z)octa-2,5-dienyl)-2(3H)-furanone) (JECFA-no: 1160) and four [FL-no: 10.034, 10.036, 10.169, 13.012] are precursors for alpha,beta-unsaturated ketones and will be considered together with other alpha,beta-unsaturated ketones and aldehydes. The Panel concluded that the remaining 11 substances in the JECFA flavouring group of alicyclic, alicyclic fused and aromatic-fused ring lactones are structurally related to the aromatic lactone in the FGE.27, as well as to a group of lactones in FGE.10 and the hydrolysis products to secondary and tertiary alcohols in FGE.09 and FGE.18, respectively. |
| Genetic Toxicity | - | - | - | EFSA shall deliver an opinion on the safety for the target animals, consumer, user and the environment and the efficacy of the active substances 3-propylidenephthalide, 3-butylidenephthalide and 3,4-dihydrocoumarin. |
Cross-Reference to Chemicals / Cosmetics / Food
Internal cross-vertical links connecting cannabis rows to chemical, cosmetics, and EFSA food/toxicology context.
SOURCE
core public cross-reference
Frequently Asked Questions
FAQ answers are generated from the same fetched cannabis, EFSA, cosmetics, and chemical rows rendered above.
SOURCE
Regulatory source
What is the regulatory limit for 3,4-Dihydrocoumarin in cannabis?
3,4-Dihydrocoumarin does not have a numeric cannabis_contaminant_tests range in the fetched page data. The current page query does not expose a separate action-limit column.
Which states test for 3,4-Dihydrocoumarin?
3,4-Dihydrocoumarin does not have state-level cannabis testing rows in the fetched page data.
What are the EFSA reference values for 3,4-Dihydrocoumarin?
3,4-Dihydrocoumarin has 19 EFSA OpenFoodTox reference value rows in the cannabis database, including MSI/FC, TTC Cramer Class III, margin of safety.
Is 3,4-Dihydrocoumarin also regulated in cosmetics or food?
3,4-Dihydrocoumarin has a cosmetics ingredient cross-reference with EU status permitted. EFSA food/toxicology context is available on this page.