Cosmetic cross-reference

Piperine

CAS 94-62-2

Piperine (CAS 94-62-2) is a Phase 2 pharmaceutical compound with 6 bioactivity targets and 2 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral / FAERS

Adverse signals

SOURCE IUPHAR / PharmGKB

PubMed IDs

SOURCE ChEMBL 36 B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

Piperine

CAS Number

94-62-2

UNII

U71XL721QK

InChIKey

MXXWOMGUGJBKIW-YPCIICBESA-N

ChEMBL ID

CHEMBL43185

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

natural product

SOURCE ChEMBL 36 B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2

Mid-stage clinical development phase from the compound identifier source.

ChEMBL CHEMBL43185 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE ChEMBL 36 activities + assays 6 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	Potency	22822.065 nM	39	-
-	IC50	27585.095263157895 nM	37	-
-	MIC	288.9219047619047 ug.mL-1	21	-
-	Ki	32700 nM	5	-
-	EC50	28340.57 nM	4	-
-	MIC	119000 nM	1	-

SOURCE IUPHAR ligand-target interactions 1 interaction

IUPHAR Ligand-Target Data

Curated ligand-target interaction rows with action, affinity, and literature identifiers.

Target	Action	Affinity	PubMed
TRPV1 TRPV1	Agonist	4.400000095367432 pEC50	15685214

SOURCE RxNorm drug names 2 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
PIPERINE	1311146	SU	MTHSPL
piperine	1311146	IN	RXNORM

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Piperine used for in pharmaceutical contexts?

Piperine (CAS 94-62-2) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Piperine?

Piperine has 2 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Drug interaction, Seizure. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Piperine also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Piperine with EU status "permitted".

What clinical phase is Piperine in?

Piperine is rendered with ChEMBL max phase 2.