Therapeutic flag Cosmetic cross-reference

Thymol

CAS 89-83-8

Thymol (CAS 89-83-8) is a Phase 2 pharmaceutical compound with 3 bioactivity targets and 1,669 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral / FAERS

Adverse signals

1,669

SOURCE IUPHAR / PharmGKB

PubMed IDs

SOURCE ChEMBL 36 B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

Thymol

CAS Number

89-83-8

UNII

3J50XA376E

InChIKey

MGSRCZKZVOBKFT-UHFFFAOYSA-N

ChEMBL ID

CHEMBL29411

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

natural producttherapeutic flag

SOURCE ChEMBL 36 B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2

Mid-stage clinical development phase from the compound identifier source.

ChEMBL CHEMBL29411 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE DailyMed SPL XML 1 label row

Drug Label Active Ingredients

Active ingredient and active moiety rows from source drug product labels.

Product	Ingredient	Active Moiety	Effective
Antispetic	THYMOL 3J50XA376E	THYMOL	20260505

SOURCE ChEMBL 36 activities + assays 11 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	MIC	113.56680851063831 ug.mL-1	47	-
-	AC50	26041.062857142857 nM	35	-
-	EC50	46695.596000000005 nM	9	-
-	EC50	19.4 nmol/cm2	3	-
-	EC50	13.593333333333334 ug.mL-1	3	-
-	Potency	14613.199999999999 nM	3	-
-	IC50	19976.309999999998 nM	1	-
-	Ki	8200 nM	1	-
Transient receptor potential cation channel subfamily A member 1 Ion channel	EC50	5.22	-	Homo sapiens
Transient receptor potential cation channel subfamily M member 8 Ion channel	EC50	4.28	-	Rattus norvegicus
Heat sensitive channel TRPV3 Unclassified	EC50	4.54	-	Rattus norvegicus

SOURCE IUPHAR ligand-target interactions 2 interactions

IUPHAR Ligand-Target Data

Curated ligand-target interaction rows with action, affinity, and literature identifiers.

Target	Action	Affinity	PubMed
TRPA1 TRPA1	Activation	4.699999809265137 pEC50	18334983
TRPV3 Trpv3	Full agonist	3.299999952316284 pEC50	16617338

SOURCE RxNorm drug names 4 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
Thymol	10553	SU	MTHSPL
THYMOL	10553	SU	MTHSPL
thymol	10553	SU	MTHSPL
thymol	10553	IN	RXNORM

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Thymol used for in pharmaceutical contexts?

Thymol (CAS 89-83-8) appears in DailyMed active-ingredient label rows, including Antispetic.

What are the known adverse events for Thymol?

Thymol has 1,669 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Abdominal discomfort, Abdominal distension, Abdominal pain, Abdominal pain upper, Acquired porphyria. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Thymol also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Thymol with EU status "permitted".

What clinical phase is Thymol in?

Thymol is rendered with ChEMBL max phase 2.

What bioactivity targets are documented for Thymol?

Thymol has 11 bioactivity rows in this page query. Rendered target entries include Transient receptor potential cation channel subfamily A member 1, Transient receptor potential cation channel subfamily M member 8, Heat sensitive channel TRPV3.