Therapeutic flag Cosmetic cross-reference

Chloroxylenol

CAS 88-04-0

Chloroxylenol (CAS 88-04-0) is a Phase 2 pharmaceutical compound with 2 bioactivity targets and 268 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral

Adverse signals

268

SOURCE IUPHAR/BPS

PubMed IDs

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

Chloroxylenol

CAS Number

88-04-0

UNII

0F32U78V2Q

InChIKey

OSDLLIBGSJNGJE-UHFFFAOYSA-N

ChEMBL ID

CHEMBL398440

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

natural producttherapeutic flag

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2

Mid-stage clinical development phase from the compound identifier source.

ChEMBL CHEMBL398440 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE EMBL-EBI ChEMBL 6 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	AC50	26517.600000000002 nM	33	-
-	Potency	39284.9 nM	20	-
-	IC50	10909.404999999999 nM	3	-
-	Ki	1181 nM	1	-
5-hydroxytryptamine receptor 2B GPCR	Ki	5.928	-	Homo sapiens
Amine oxidase [flavin-containing] A Enzyme	IC50	5.738	-	Homo sapiens

SOURCE DrugCentral 80 associations

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PT	Drug AE	LLR	MedDRA
Completed suicide	4110	11153.516	10010144
Drug abuse	3199	8984.232	10013654
Toxicity to various agents	4165	8708.815	10070863
Intentional overdose	1126	2358.872	10022523
Cardio-respiratory arrest	1051	2178.362	10007617
Overdose	1149	1774.808	10033295
Suicide attempt	763	1449.65	10042464
Alcohol interaction	309	1195.482	10001597
Intentional product misuse	615	1010.103	10074903
Suspected suicide	323	1000.573	10082458
Alcohol abuse	267	925.552	10001584
Alcohol poisoning	208	711.148	10001605
Respiratory arrest	352	583.156	10038669
Coma	440	562.32	10010071
Drug dependence	313	544.473	10013663
Exposure to toxic agent	179	511.441	10053487
Cardiac arrest	509	496.743	10007515
Substance abuse	190	484.247	10066169
Death	1066	457.749	10011906
Alcohol use	140	427.725	10048921
Drug ineffective	109	389.069	10013709
Poisoning deliberate	181	379.2	10036000
Aggression	251	329.58	10001488
Asphyxia	136	295.114	10003497
Respiratory depression	175	280.165	10038678
Diarrhoea	77	277.954	10012735
Pain	62	250.587	10033371
Agitation	285	250.473	10001497
Poisoning	151	247.655	10061355
Fatigue	134	246.67	10016256
Arthralgia	39	221.181	10003239
Blood alcohol increased	62	219.942	10060013
Somnolence	437	217.005	10041349
Rash	48	213.878	10037844
Intentional self-injury	157	205.605	10022524
Suicidal ideation	240	204.923	10042458
Mydriasis	120	204.071	10028521
Drug use disorder	92	192.96	10079381
Loss of consciousness	328	192.415	10024855
Off label use	165	187.924	10053762
Dyspnoea	121	181.22	10013968
Drug interaction	534	180.385	10013710
Drug withdrawal syndrome	152	171.121	10013754
Pyrexia	75	169.289	10037660
Depressed level of consciousness	220	168.398	10012373
Substance use disorder	46	165.564	10079384
Pneumonia	81	163.92	10035664
Joint swelling	4	162.615	10023232
Alcoholism	66	162.383	10001639
Anaemia	27	152.962	10002034

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE NLM RxNorm 3 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
CHLOROXYLENOL	20877	SU	MTHSPL
Chloroxylenol	20877	SU	MTHSPL
chloroxylenol	20877	IN	RXNORM

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Chloroxylenol used for in pharmaceutical contexts?

Chloroxylenol (CAS 88-04-0) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Chloroxylenol?

Chloroxylenol has 268 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Completed suicide, Drug abuse, Toxicity to various agents, Intentional overdose, Cardio-respiratory arrest. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Chloroxylenol also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Chloroxylenol (PCMX) with EU status "restricted".

What clinical phase is Chloroxylenol in?

Chloroxylenol is rendered with ChEMBL max phase 2.

What bioactivity targets are documented for Chloroxylenol?

Chloroxylenol has 6 bioactivity rows in this page query. Rendered target entries include 5-hydroxytryptamine receptor 2B, Amine oxidase [flavin-containing] A.