ParenteralTopicalDosed ingredient
Cosmetic cross-reference
Alcohol
CAS 64-17-5
Alcohol (CAS 64-17-5) is a Phase 4 pharmaceutical compound with 4 bioactivity targets and 1,495 adverse event associations.
SOURCE
NLM DailyMed
Label records
3
SOURCE
EMBL-EBI ChEMBL
Bioactivity
8
SOURCE
DrugCentral / FAERS
Adverse signals
1,495
SOURCE
IUPHAR / PharmGKB
PubMed IDs
30
SOURCE
ChEMBL 36
B25820EEF0F0
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Primary Name
Alcohol
CAS Number
64-17-5
UNII
3K9958V90M
InChIKey
LFQSCWFLJHTTHZ-UHFFFAOYSA-N
ChEMBL ID
CHEMBL545
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
Synonyms and normalized names
DEHYDRATED ALCOHOLethanol
dosed ingredientnatural productparenteraltopical
SOURCE
ChEMBL 36
B25820EEF0F0
Clinical Development Phase
Highest clinical development phase rendered from the matched compound identifier rows.
Phase 4 (Approved)
Approved or marketed human pharmaceutical use is represented in the source phase field.
ChEMBL CHEMBL545 | Small molecule
SOURCE
Ingredients table / CosIng profile
same-CAS cross-reference
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
SOURCE
DailyMed SPL XML
3 label rows
Drug Label Active Ingredients
Active ingredient and active moiety rows from source drug product labels.
| Product | Ingredient | Active Moiety | Effective |
|---|---|---|---|
| Boo Crew Hand Care Essentials | ALCOHOL 3K9958V90M |
ALCOHOL | 20260505 |
| Scentfull Cashmere Vanilla Hand Sanitizer | ALCOHOL 3K9958V90M |
ALCOHOL | 20260504 |
| Scentfull Frosted Woods Hand Sanitizer | ALCOHOL 3K9958V90M |
ALCOHOL | 20260504 |
SOURCE
ChEMBL 36 activities + assays
8 bioactivity rows
Bioactivity & Target Interactions
Target-level activity records with assay counts, activity type, and measured value where present.
| Target | Activity | Value | Assays | Organism |
|---|---|---|---|---|
| - | IC50 | 174.9815384615385 | 26 | - |
| - | EC50 | 19.555555555555557 % | 9 | - |
| - | Potency | 22130.483333333334 nM | 6 | - |
| - | MIC | 2.25 % | 4 | - |
| Glycine receptor subunit alpha-1 Ion channel |
- | - | - | Homo sapiens |
| Glycine receptor subunit alpha-2 Ion channel |
- | - | - | Homo sapiens |
| Glutamate receptor ionotropic, NMDA 3A Ion channel |
- | - | - | Homo sapiens |
| GABA A receptor alpha-4/beta-2/delta Ion channel |
- | - | - | Homo sapiens |
SOURCE
DrugCentral 2023 / FAERS disproportionality
80 associations
Adverse Event Associations
DrugCentral / FAERS disproportionality signal rows matched to this compound.
| Reaction PT | Drug AE | LLR | MedDRA |
|---|---|---|---|
| Completed suicide | 6723 | 16401.578 | 10010144 |
| Drug abuse | 5073 | 12708.955 | 10013654 |
| Toxicity to various agents | 6272 | 10938.906 | 10070863 |
| Cardio-respiratory arrest | 1821 | 3402.864 | 10007617 |
| Intentional overdose | 1622 | 2783.708 | 10022523 |
| Overdose | 1774 | 2210.486 | 10033295 |
| Respiratory arrest | 1079 | 2150.049 | 10038669 |
| Intentional product misuse | 1205 | 1878.263 | 10074903 |
| Poisoning | 742 | 1801.389 | 10061355 |
| Cardiac arrest | 1323 | 1508.963 | 10007515 |
| Suicide attempt | 1007 | 1457.993 | 10042464 |
| Alcohol interaction | 355 | 1153.655 | 10001597 |
| Alcohol abuse | 343 | 1015.46 | 10001584 |
| Alcohol poisoning | 323 | 1001.317 | 10001605 |
| Death | 2223 | 912.788 | 10011906 |
| Alcohol use | 291 | 880.072 | 10048921 |
| Exposure via ingestion | 261 | 796.309 | 10073302 |
| Suspected suicide | 325 | 766.397 | 10082458 |
| Coma | 633 | 591.059 | 10010071 |
| Substance abuse | 264 | 562.301 | 10066169 |
| Drug dependence | 407 | 522.112 | 10013663 |
| Poisoning deliberate | 280 | 500.102 | 10036000 |
| Diarrhoea | 281 | 412.747 | 10012735 |
| Drug hypersensitivity | 1080 | 411.559 | 10013700 |
| Exposure to toxic agent | 180 | 382.171 | 10053487 |
| Blood alcohol increased | 108 | 360.906 | 10060013 |
| Asphyxia | 195 | 348.763 | 10003497 |
| Pneumonia | 183 | 337.785 | 10035664 |
| Anaemia | 67 | 308.925 | 10002034 |
| Drug ineffective | 660 | 298.199 | 10013709 |
| Fatigue | 499 | 283.384 | 10016256 |
| Off label use | 479 | 271.374 | 10053762 |
| Neutropenia | 22 | 258.567 | 10029354 |
| Aggression | 308 | 257.596 | 10001488 |
| Nausea | 476 | 257.513 | 10028813 |
| Respiratory depression | 225 | 257.008 | 10038678 |
| Methaemoglobinaemia | 121 | 245.626 | 10027496 |
| Accidental death | 97 | 206.79 | 10063746 |
| Disease progression | 7 | 206.437 | 10061818 |
| Cough | 88 | 206.043 | 10011224 |
| Mydriasis | 159 | 200.842 | 10028521 |
| Agitation | 382 | 197.894 | 10001497 |
| Product dose omission issue | 47 | 195.965 | 10084406 |
| Dyspnoea | 444 | 193.696 | 10013968 |
| Asthenia | 188 | 193.527 | 10003549 |
| Intentional self-injury | 212 | 193.262 | 10022524 |
| Drug abuser | 106 | 191.9 | 10061111 |
| Febrile neutropenia | 22 | 180.125 | 10016288 |
| Alcoholism | 89 | 179.351 | 10001639 |
| Headache | 340 | 173.249 | 10019211 |
Association rows are source-linked signal records, not incidence rates or clinical causality claims.
SOURCE
IUPHAR ligand-target interactions
6 interactions
IUPHAR Ligand-Target Data
Curated ligand-target interaction rows with action, affinity, and literature identifiers.
| Target | Action | Affinity | PubMed |
|---|---|---|---|
| 5-HT 3 A Htr3a |
Positive | - | 16257471|7541281|9518697|16520747 |
| Glycine Receptor (All subtypes) | Potentiation | - | 8700149 |
| K ir 3.1 Kcnj3 |
Agonist | - | 10570485|10570486 |
| K ir 3.2 | Agonist | - | 10570485|10570486|19561601 |
| K ir 3.4 Kcnj5 |
Activator | - | 10570485|10570486 |
| TRPV6 TRPV6 |
Activation | 0.8199999928474426 pEC50 | 35705057 |
SOURCE
PharmGKB drug-gene phenotypes
60 phenotype rows
Pharmacogenomics
Drug-gene phenotype annotations and evidence levels from PharmGKB-mapped rows.
PDE4B (PA33129) rs6421482
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs61767420
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs1402398
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
GCKR (PA28611) rs1260326
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
- rs494904
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
- rs9679319
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
THSD7B (PA162405776) rs13382553
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs2673136
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
ADH1B (PA24571) rs75967634
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
SLC39A8 (PA134931507) rs13135092
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
CADM2 (PA162380882) rs62250713
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs13129401
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
ADH1B (PA24571) rs1229984
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
ADH1C (PA24572) rs13125415
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
DPP6 (PA27468) rs2533200
Allele C is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs2582405
Allele T is associated with increased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
- rs7900002
Allele T is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs56722963
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
MED19 (PA134926032),"TMX2 (PA164726611)" rs576859
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
- rs6589386
Allele T is associated with decreased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
- rs1783835
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
ARID4A (PA34249) rs61974485
Allele T is associated with increased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
SLC4A8 (PA35900) rs12296477
Allele C is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
TNRC6A (PA36656) rs72768626
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
FTO (PA152208656) rs9937709
Allele A is associated with increased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
FUT2 (PA28429) rs492602
Allele A is associated with decreased risk of Alcoholism due to ethanol as compared to allele G.
Evidence: -; PMID 32451486
- rs8008020
Allele T is associated with increased risk of Alcoholism due to ethanol as compared to allele C.
Evidence: -; PMID 32451486
OPRM1 (PA31945) rs1799971
Genotype AG is associated with increased risk of Substance-Related Disorders due to 3,4-methylenedioxymethamphetamine, cocaine, ethanol or opioids as compared to genotype AA.
Evidence: -; PMID 31246565
OPRM1 (PA31945) rs1799971
Genotypes AG + GG are not associated with dose of ethanol in children as compared to genotype AA.
Evidence: -; PMID 24134200
OPRM1 (PA31945) rs1799971
Allele G is associated with increased risk of Alcoholism due to ethanol in children as compared to allele A.
Evidence: -; PMID 19860800
SOURCE
RxNorm drug names
5 name rows
Drug Names / RxNorm
Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.
| Name | RxCUI | Type | Source |
|---|---|---|---|
| DEHYDRATED ALCOHOL | 448 | SU | MTHSPL |
| Alcohol | 448 | SU | MTHSPL |
| ALCOHOL | 448 | SU | MTHSPL |
| alcohol | 448 | SU | MTHSPL |
| ethanol | 448 | IN | RXNORM |
SOURCE
Rendered pharma page rows
FAQPage JSON-LD
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Alcohol used for in pharmaceutical contexts?
Alcohol (CAS 64-17-5) appears in DailyMed active-ingredient label rows, including Boo Crew Hand Care Essentials, Scentfull Cashmere Vanilla Hand Sanitizer, Scentfull Frosted Woods Hand Sanitizer.
What are the known adverse events for Alcohol?
Alcohol has 1,495 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Completed suicide, Drug abuse, Toxicity to various agents, Cardio-respiratory arrest, Intentional overdose. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Alcohol also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for Alcohol Denat with EU status "permitted".
What clinical phase is Alcohol in?
Alcohol is rendered with ChEMBL max phase 4 (approved).
What bioactivity targets are documented for Alcohol?
Alcohol has 8 bioactivity rows in this page query. Rendered target entries include Glycine receptor subunit alpha-1, Glycine receptor subunit alpha-2, Glutamate receptor ionotropic, NMDA 3A, GABA A receptor alpha-4/beta-2/delta.