Cosmetic cross-reference

58-95-7

CAS 58-95-7

58-95-7 (CAS 58-95-7) is a pharmaceutical compound with 2 bioactivity targets and 1,660 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral

Adverse signals

1,660

SOURCE IUPHAR/BPS

PubMed IDs

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

58-95-7

CAS Number

58-95-7

UNII

A7E6112E4N

InChIKey

ZAKOWWREFLAJOT-CEFNRUSXSA-N

ChEMBL ID

CHEMBL1047

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

Synonyms and normalized names

.ALPHA.-TOCOPHEROL ACETATE, D-

natural product

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE EMBL-EBI ChEMBL 2 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	AC50	28584.435294117648 nM	34	-
-	Potency	12127.633333333333 nM	3	-

SOURCE DrugCentral 80 associations

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PT	Drug AE	LLR	MedDRA
Pemphigus	5388	2458.639	10034280
Systemic lupus erythematosus	5719	2366.662	10042945
Glossodynia	4953	2068.877	10018388
Hand deformity	4329	1743.826	10061194
Arthropathy	5567	1591.008	10003285
Rheumatoid arthritis	5937	1571.985	10039073
Alopecia	6758	1483.255	10001760
Abdominal discomfort	6877	1425.416	10000059
Wound	4193	1415.851	10052428
Maternal exposure during pregnancy	4761	1367.21	10071408
Synovitis	4241	1185.451	10042868
Contraindicated product administered	4776	1084.925	10078504
Anti-cyclic citrullinated peptide antibody positive	2940	1079.645	10068798
Joint swelling	6402	1060.664	10023232
Swelling	5515	1039.592	10042674
Discomfort	3826	1018.502	10013082
Pericarditis	3239	1004.76	10034484
Infusion related reaction	5398	952.783	10051792
Completed suicide	4249	944.307	10010144
Drug abuse	3290	915.677	10013654
Pain	12164	910.682	10033371
Arthralgia	9663	708.373	10003239
Duodenal ulcer perforation	2093	678.471	10013849
Helicobacter infection	2162	654.173	10054263
Rheumatoid factor positive	1969	647.645	10039080
Psoriatic arthropathy	2239	607.751	10037162
Febrile neutropenia	804	606.711	10016288
Exposure during pregnancy	3043	606.434	10073513
Hepatic enzyme increased	3904	588.339	10060795
Acute kidney injury	2699	562.134	10069339
Drug interaction	1987	559.426	10013710
Musculoskeletal stiffness	3665	544.919	10052904
Product use issue	4462	541.488	10076309
Drug intolerance	5228	487.879	10061822
Therapeutic product effect decreased	3536	457.316	10082201
Death	4425	449.339	10011906
Disease progression	877	442.345	10061818
Neutropenia	1634	358.809	10029354
Knee arthroplasty	1264	355.027	10023469
Nasopharyngitis	4334	349.62	10028810
Alcohol interaction	313	339.901	10001597
Hip arthroplasty	1127	336.459	10020096
Malignant neoplasm progression	571	327.788	10051398
Foetal exposure during pregnancy	1868	326.829	10071404
Treatment failure	3517	304.362	10066901
Rheumatic fever	970	297.142	10039054
Hypersensitivity	4569	296.713	10020751
Impaired healing	1921	296.62	10021519
Renal failure	1111	287.102	10038435
Drug reaction with eosinophilia and systemic symptoms	108	277.611	10073508

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE NLM RxNorm 1 name row

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
.ALPHA.-TOCOPHEROL ACETATE, D-	1441649	SU	MTHSPL

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is 58-95-7 used for in pharmaceutical contexts?

58-95-7 (CAS 58-95-7) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for 58-95-7?

58-95-7 has 1,660 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Pemphigus, Systemic lupus erythematosus, Glossodynia, Hand deformity, Arthropathy. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is 58-95-7 also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Tocopheryl Acetate with EU status "permitted".

What clinical phase is 58-95-7 in?

No phase 1-4 clinical development badge is rendered for 58-95-7 because the matched compound identifier rows do not contain a max-phase value.