Cosmetic cross-reference

Arbutin

CAS 497-76-7

Arbutin (CAS 497-76-7) is a Phase 2 pharmaceutical compound with 2 bioactivity targets and 0 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
9
SOURCE DrugCentral
Adverse signals
0
SOURCE IUPHAR/BPS
PubMed IDs
0
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Arbutin
CAS Number
497-76-7
UNII
C5INA23HXF
InChIKey
BJRNKVDFDLYUGJ-RMPHRYRLSA-N
ChEMBL ID
CHEMBL232202
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
natural product
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2
Mid-stage clinical development phase from the compound identifier source.
ChEMBL CHEMBL232202 | Small molecule
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

SOURCE EMBL-EBI ChEMBL 9 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- IC50 49401.885 nM 11 -
- AC50 2990.3500000000004 nM 2 -
- Potency 1205.45 nM 2 -
- IC50 2300 ppm 1 -
- IC50 25 ug.mL-1 1 -
- MIC 500 ug.mL-1 1 -
Tyrosinase
Enzyme
IC50 4.52 - Homo sapiens
Polyphenol oxidase 2
Enzyme
IC50 4 - Agaricus bisporus
Tyrosinase
Enzyme
IC50 4.52 - Mus musculus
SOURCE NLM RxNorm 2 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

NameRxCUI TypeSource
ARBUTIN 1367175 SU MTHSPL
arbutin 1367175 IN RXNORM
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Arbutin used for in pharmaceutical contexts?

Arbutin (CAS 497-76-7) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Arbutin?

No adverse-event association or SIDER side-effect rows are rendered for Arbutin in this page query. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Arbutin also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Arbutin with EU status "restricted".

What clinical phase is Arbutin in?

Arbutin is rendered with ChEMBL max phase 2.

What bioactivity targets are documented for Arbutin?

Arbutin has 9 bioactivity rows in this page query. Rendered target entries include Tyrosinase, Polyphenol oxidase 2.