Cosmetic cross-reference

(-)-Epicatechin

CAS 490-46-0

(-)-Epicatechin (CAS 490-46-0) is a Phase 2 pharmaceutical compound with 9 bioactivity targets and 0 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral

Adverse signals

SOURCE IUPHAR/BPS

PubMed IDs

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

(-)-Epicatechin

CAS Number

490-46-0

UNII

34PHS7TU43

InChIKey

PFTAWBLQPZVEMU-UKRRQHHQSA-N

ChEMBL ID

CHEMBL583912

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

natural product

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2

Mid-stage clinical development phase from the compound identifier source.

ChEMBL CHEMBL583912 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE EMBL-EBI ChEMBL 9 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	IC50	119733.125 nM	40	-
-	Potency	21156.129032258064 nM	25	-
-	MIC	118.2 ug.mL-1	20	-
-	IC50	20.208000000000002 ug.mL-1	15	-
-	EC50	33680.4 nM	5	-
-	AC50	15458.112500000001 nM	4	-
-	Ki	66733.33333333333 nM	3	-
-	Kd	39950 nM	2	-
-	MIC	1000000 nM	1	-

SOURCE IUPHAR/BPS 1 interaction

IUPHAR Ligand-Target Data

Curated ligand-target interaction rows with action, affinity, and literature identifiers.

Target	Action	Affinity	PubMed
TAS2R39 TAS2R39	Agonist	3.380000114440918 pEC50	21272567

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is (-)-Epicatechin used for in pharmaceutical contexts?

(-)-Epicatechin (CAS 490-46-0) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for (-)-Epicatechin?

No adverse-event association or SIDER side-effect rows are rendered for (-)-Epicatechin in this page query. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is (-)-Epicatechin also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Epicatechin with EU status "permitted".

What clinical phase is (-)-Epicatechin in?

(-)-Epicatechin is rendered with ChEMBL max phase 2.