Macrogol
CAS 25322-68-3
Macrogol (CAS 25322-68-3) is a pharmaceutical compound with 0 bioactivity targets and 12,812 adverse event associations.
Compound Identity
Matched identifiers and naming fields for the pharmaceutical compound record.
Cross-Reference to Cosmetics
Same-CAS ingredient record found in the cosmetics vertical.
Adverse Event Associations
DrugCentral / FAERS disproportionality signal rows matched to this compound.
| Reaction PT | Drug AE | LLR | MedDRA |
|---|---|---|---|
| Constipation | 1485 | 655.544 | 10010774 |
| Macular degeneration | 301 | 354.722 | 10025409 |
| Infective pulmonary exacerbation of cystic fibrosis | 230 | 350.375 | 10070608 |
| Contraindicated product administered | 16 | 294.261 | 10078504 |
| Febrile neutropenia | 895 | 283.98 | 10016288 |
| Synovitis | 8 | 254.049 | 10042868 |
| Pemphigus | 6 | 250.043 | 10034280 |
| Systemic lupus erythematosus | 22 | 235.119 | 10042945 |
| Treatment failure | 43 | 227.363 | 10066901 |
| Appendicolith | 140 | 219.754 | 10074458 |
| Hand deformity | 6 | 214.648 | 10061194 |
| Rheumatoid arthritis | 78 | 209.129 | 10039073 |
| Abdominal pain | 1181 | 202.03 | 10000081 |
| Drug ineffective | 1260 | 195.27 | 10013709 |
| Abdominal distension | 520 | 185.803 | 10000060 |
| Maternal exposure during pregnancy | 50 | 179.043 | 10071408 |
| Completed suicide | 52 | 176.19 | 10010144 |
| Arthropathy | 84 | 167.483 | 10003285 |
| Glossodynia | 36 | 162.931 | 10018388 |
| Aplastic anaemia | 163 | 162.774 | 10002967 |
| Urinary tract infection | 891 | 158.378 | 10046571 |
| Drug intolerance | 178 | 156.769 | 10061822 |
| Appendicitis | 165 | 138.391 | 10003011 |
| Therapeutic product effect decreased | 78 | 136.77 | 10082201 |
| Pericarditis | 23 | 136.674 | 10034484 |
| Joint swelling | 214 | 131.369 | 10023232 |
| Dehydration | 757 | 130.205 | 10012174 |
| Sepsis | 822 | 128.083 | 10040047 |
| Hyponatraemia | 554 | 122.621 | 10021036 |
| Alopecia | 206 | 121.576 | 10001760 |
| Plasma cell myeloma | 293 | 119.379 | 10035226 |
| Wound | 56 | 118.534 | 10052428 |
| Exposure during pregnancy | 47 | 117.82 | 10073513 |
| Chronic sinusitis | 122 | 109.397 | 10009137 |
| Fall | 1238 | 109.004 | 10016173 |
| Toxicity to various agents | 304 | 101.579 | 10070863 |
| Blood calcium decreased | 181 | 100.025 | 10005395 |
| Drug interaction | 305 | 99.626 | 10013710 |
| Helicobacter infection | 13 | 98.202 | 10054263 |
| Arthralgia | 620 | 97.132 | 10003239 |
| Nausea | 2199 | 97.026 | 10028813 |
| Discomfort | 77 | 95.264 | 10013082 |
| Psoriatic arthropathy | 20 | 94.499 | 10037162 |
| Hypersensitivity | 228 | 93.55 | 10020751 |
| Foetal exposure during pregnancy | 22 | 90.769 | 10071404 |
| Folliculitis | 5 | 90.428 | 10016936 |
| Blood phosphorus increased | 91 | 88.356 | 10050196 |
| Sedation complication | 112 | 87.876 | 10079741 |
| Creatinine renal clearance decreased | 124 | 87.119 | 10011372 |
| Mental status changes | 260 | 86.916 | 10048294 |
Association rows are source-linked signal records, not incidence rates or clinical causality claims.
Drug Names / RxNorm
Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.
| Name | RxCUI | Type | Source |
|---|---|---|---|
| PEG-75 | 221147 | SU | MTHSPL |
| polyethylene glycol 3350 | 221147 | SU | MTHSPL |
| Polyethylene Glycol 3350 | 221147 | SU | MTHSPL |
| POLYETHYLENE GLYCOL 3350 | 221147 | SU | MTHSPL |
| Polyethylene glycol 3350 | 221147 | SU | MTHSPL |
| macrogol | 8516 | SY | RXNORM |
Frequently Asked Questions
Short answers generated only from the same visible source-linked rows on this page.
What is Macrogol used for in pharmaceutical contexts?
Macrogol (CAS 25322-68-3) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.
What are the known adverse events for Macrogol?
Macrogol has 12,812 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Constipation, Macular degeneration, Infective pulmonary exacerbation of cystic fibrosis, Contraindicated product administered, Febrile neutropenia. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.
Is Macrogol also used in cosmetics?
Yes. The ingredients table has a same-CAS cosmetic profile for PEG-200 with EU status "permitted".
What clinical phase is Macrogol in?
No phase 1-4 clinical development badge is rendered for Macrogol because the matched compound identifier rows do not contain a max-phase value.