ParenteralTopical Cosmetic cross-reference

Fluorescein

CAS 2321-07-5

Fluorescein (CAS 2321-07-5) is a Phase 4 pharmaceutical compound with 4 bioactivity targets and 0 adverse event associations.

SOURCE NLM DailyMed

Label records

SOURCE EMBL-EBI ChEMBL

Bioactivity

SOURCE DrugCentral

Adverse signals

SOURCE IUPHAR/BPS

PubMed IDs

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name

Fluorescein

CAS Number

2321-07-5

UNII

TPY09G7XIR

InChIKey

GNBHRKFJIUUOQI-UHFFFAOYSA-N

ChEMBL ID

CHEMBL1057

Molecule Type

Small molecule

Source Match

EMBL-EBI ChEMBL (INCHIKEY)

natural productparenteraltopical

SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 4 (Approved)

Approved or marketed human pharmaceutical use is represented in the source phase field.

ChEMBL CHEMBL1057 | Small molecule

SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

This substance also has a cosmetic safety profile →

SOURCE EMBL-EBI ChEMBL 8 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

Target	Activity	Value	Assays	Organism
-	Potency	29974.124074074072 nM	25	-
-	IC50	20665.047777777778 nM	7	-
-	Ki	51237.8025 nM	2	-
-	EC50	19500 nM	1	-
Cytochrome P450 2C19 Enzyme	IC50	6.042	-	Homo sapiens
Protein arginine N-methyltransferase 1 Enzyme	IC50	4.12	-	Homo sapiens
Solute carrier family 22 member 6 Transporter	Ki	5.53	-	Mus musculus
Solute carrier family 22 member 20 Transporter	Ki	4	-	Mus musculus

SOURCE DrugCentral 8 associations

Adverse Event Associations

DrugCentral / FAERS disproportionality signal rows matched to this compound.

Reaction PT	Drug AE	LLR	MedDRA
Anaphylactic shock	76	301.351	10002199
Anaphylactic reaction	40	96.024	10002198
Chest discomfort	34	60.643	10008469
Haemangioma congenital	11	59.753	10018818
Urticaria	37	57.162	10046735
Pruritus	49	53.458	10037087
Histamine level increased	7	52.556	10060051
Cold sweat	17	51.699	10009866

Association rows are source-linked signal records, not incidence rates or clinical causality claims.

SOURCE NLM RxNorm 4 name rows

Drug Names / RxNorm

Normalized drug-name vocabulary rows, RxCUIs, and source abbreviations.

Name	RxCUI	Type	Source
FLUORESCEIN	25138	SU	MTHSPL
Fluorescein	25138	SU	MTHSPL
fluorescein	25138	SU	MTHSPL
fluorescein	25138	IN	RXNORM

SOURCE SIDER 80 side-effect rows

Side Effects

SIDER side-effect terms mapped to the drug or same-CAS compound identity.

Side Effect	Drug Name	MedDRA Type	Concept ID
Abdominal discomfort	fluorescein	LLT	C0232487
Abdominal discomfort	fluorescein	PT	C0232487
Abdominal discomfort	fluorescein	PT	C0232487
Abdominal pain	fluorescein	LLT	C0000737
Abdominal pain	fluorescein	PT	C0000737
Ache	fluorescein	LLT	C0234238
Acute myocardial infarction	fluorescein	LLT	C0155626
Acute myocardial infarction	fluorescein	PT	C0155626
Anaphylactic shock	fluorescein	LLT	C0002792
Anaphylactic shock	fluorescein	PT	C0002792
Anaphylactic shock	fluorescein	PT	C0002792
Anaphylactoid reaction	fluorescein	LLT	C0340865
Anaphylactoid reaction	fluorescein	PT	C0340865
Angina pectoris	fluorescein	LLT	C0002962
Angina pectoris	fluorescein	PT	C0002962
Angiopathy	fluorescein	LLT	C0042373
Angiopathy	fluorescein	PT	C0042373
Aphasia	fluorescein	PT	C0003537
Asthenia	fluorescein	LLT	C0004093
Asthenia	fluorescein	PT	C0004093
Asthma	fluorescein	LLT	C0004096
Asthma	fluorescein	PT	C0004096
Basilar artery syndrome	fluorescein	LLT	C0004812
Bradycardia	fluorescein	LLT	C0428977
Bradycardia	fluorescein	PT	C0428977
Bronchospasm	fluorescein	LLT	C0006266
Bronchospasm	fluorescein	PT	C0006266
Cardiac arrest	fluorescein	LLT	C0018790
Cardiac arrest	fluorescein	PT	C0018790
Cardiac disorder	fluorescein	LLT	C0018799
Cardiac disorder	fluorescein	PT	C0018799
Cerebrovascular accident	fluorescein	LLT	C0038454
Cerebrovascular accident	fluorescein	PT	C0038454
Chest pain	fluorescein	LLT	C0008031
Chest pain	fluorescein	PT	C0008031
Chills	fluorescein	LLT	C0085593
Chills	fluorescein	PT	C0085593
Chromaturia	fluorescein	PT	C0541832
Cold sweat	fluorescein	LLT	C0232431
Cold sweat	fluorescein	PT	C0232431
Convulsion	fluorescein	LLT	C0036572
Convulsion	fluorescein	PT	C0036572
Cough	fluorescein	LLT	C0010200
Cough	fluorescein	PT	C0010200
Dermatitis	fluorescein	LLT	C0011603
Dermatitis	fluorescein	PT	C0011603
Dermatitis	fluorescein	PT	C0011603
Diabetic retinopathy	fluorescein	LLT	C0011884
Diabetic retinopathy	fluorescein	PT	C0011884
Discomfort	fluorescein	PT	C0234215
Distress gastrointestinal	fluorescein	LLT	C0548823
Dizziness	fluorescein	LLT	C0012833
Dizziness	fluorescein	PT	C0012833
Dizziness	fluorescein	PT	C0012833
Dysgeusia	fluorescein	LLT	C0013378
Dysgeusia	fluorescein	PT	C0013378
Dysphasia	fluorescein	LLT	C0973461
Dyspnoea	fluorescein	LLT	C0013404
Dyspnoea	fluorescein	PT	C0013404
Eczema	fluorescein	LLT	C0013595
Eczema	fluorescein	PT	C0013595
Erythema	fluorescein	LLT	C0041834
Erythema	fluorescein	PT	C0041834
Extravasation	fluorescein	LLT	C0015376
Extravasation	fluorescein	PT	C0015376
Feeling abnormal	fluorescein	PT	C1443060
Feeling hot	fluorescein	LLT	C2939147
Feeling hot	fluorescein	PT	C2939147
Gastrointestinal disorder	fluorescein	LLT	C0017178
Gastrointestinal disorder	fluorescein	PT	C0017178
Gastrointestinal pain	fluorescein	PT	C0687713
Headache	fluorescein	LLT	C0018681
Headache	fluorescein	PT	C0018681
Hot flush	fluorescein	LLT	C0600142
Hot flush	fluorescein	PT	C0600142
Hyperhidrosis	fluorescein	LLT	C0020458
Hyperhidrosis	fluorescein	PT	C0020458
Hypersensitivity	fluorescein	LLT	C0020517
Hypersensitivity	fluorescein	PT	C0020517
Hypertension	fluorescein	LLT	C0020538

SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Fluorescein used for in pharmaceutical contexts?

Fluorescein (CAS 2321-07-5) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Fluorescein?

Fluorescein has 0 DrugCentral/FAERS adverse event associations. Rendered reaction terms include Anaphylactic shock, Anaphylactic reaction, Chest discomfort, Haemangioma congenital, Urticaria. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Fluorescein also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Acid Yellow 73 with EU status "restricted".

What clinical phase is Fluorescein in?

Fluorescein is rendered with ChEMBL max phase 4 (approved).

What bioactivity targets are documented for Fluorescein?

Fluorescein has 4 bioactivity rows in this page query. Rendered target entries include Cytochrome P450 2C19, Protein arginine N-methyltransferase 1, Solute carrier family 22 member 6, Solute carrier family 22 member 20.