Cosmetic cross-reference

Thiram

CAS 137-26-8

Thiram (CAS 137-26-8) is a Phase 2 pharmaceutical compound with 13 bioactivity targets and 0 adverse event associations.

SOURCE NLM DailyMed
Label records
0
SOURCE EMBL-EBI ChEMBL
Bioactivity
22
SOURCE DrugCentral
Adverse signals
0
SOURCE IUPHAR/BPS
PubMed IDs
0
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Compound Identity

Matched identifiers and naming fields for the pharmaceutical compound record.

Primary Name
Thiram
CAS Number
137-26-8
UNII
0D771IS0FH
InChIKey
KUAZQDVKQLNFPE-UHFFFAOYSA-N
ChEMBL ID
CHEMBL120563
Molecule Type
Small molecule
Source Match
EMBL-EBI ChEMBL (INCHIKEY)
natural product
SOURCE EMBL-EBI ChEMBL B25820EEF0F0

Clinical Development Phase

Highest clinical development phase rendered from the matched compound identifier rows.

Phase 2
Mid-stage clinical development phase from the compound identifier source.
ChEMBL CHEMBL120563 | Small molecule
SOURCE Ingredients table / CosIng profile same-CAS cross-reference

Cross-Reference to Cosmetics

Same-CAS ingredient record found in the cosmetics vertical.

SOURCE EMBL-EBI ChEMBL 22 bioactivity rows

Bioactivity & Target Interactions

Target-level activity records with assay counts, activity type, and measured value where present.

TargetActivity ValueAssaysOrganism
- Potency 14324.381065088757 nM 138 -
- GI50 23576.631640625 nM 70 -
- IC50 14234.699999999999 nM 28 -
- MIC 20800 nM 7 -
- AC50 5034.183333333333 nM 6 -
- EC50 13.833333333333334 ug.mL-1 3 -
- EC50 143 nM 2 -
- Kd 47000 nM 2 -
- IC50 0.76 1 -
Fructose-1,6-bisphosphatase 1
Enzyme
IC50 5.64 - Homo sapiens
Fatty-acid amide hydrolase 1
Enzyme
IC50 4.35 - Homo sapiens
Aldehyde dehydrogenase, mitochondrial
Enzyme
IC50 6.5 - Homo sapiens
Retinal dehydrogenase 1
Enzyme
IC50 7.7 - Homo sapiens
Gamma-butyrobetaine dioxygenase
Enzyme
IC50 5.24 - Homo sapiens
Monoglyceride lipase
Enzyme
IC50 6.01 - Homo sapiens
Bifunctional protein GlmU
Enzyme
IC50 4.05 - Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
Protein-lysine 6-oxidase
Enzyme
IC50 5.98 - Homo sapiens
Lysyl oxidase homolog 3
Enzyme
IC50 6.96 - Homo sapiens
Lysyl oxidase homolog 4
Enzyme
IC50 6.75 - Homo sapiens
Histone-lysine N-methyltransferase EHMT2
Enzyme
IC50 6.26 - Homo sapiens
Histone-lysine N-methyltransferase EHMT1
Enzyme
IC50 5.96 - Homo sapiens
Lysyl oxidase homolog 2
Enzyme
IC50 6.77 - Homo sapiens
SOURCE Rendered pharma page rows FAQPage JSON-LD

Frequently Asked Questions

Short answers generated only from the same visible source-linked rows on this page.

What is Thiram used for in pharmaceutical contexts?

Thiram (CAS 137-26-8) is rendered as a pharmaceutical compound from the matched source rows; no DailyMed product-name rows are present in this page query.

What are the known adverse events for Thiram?

No adverse-event association or SIDER side-effect rows are rendered for Thiram in this page query. Signal rows are source-linked records and should not be read as incidence rates or causality conclusions.

Is Thiram also used in cosmetics?

Yes. The ingredients table has a same-CAS cosmetic profile for Thiram with EU status "prohibited".

What clinical phase is Thiram in?

Thiram is rendered with ChEMBL max phase 2.

What bioactivity targets are documented for Thiram?

Thiram has 22 bioactivity rows in this page query. Rendered target entries include Fructose-1,6-bisphosphatase 1, Fatty-acid amide hydrolase 1, Aldehyde dehydrogenase, mitochondrial, Retinal dehydrogenase 1, Gamma-butyrobetaine dioxygenase.