NOAEL Studies Emollient

Zinc Stearate NOAEL Studies

INCI: ZINC STEARATE

CAS: 557-05-1

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_inhalation 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_inhalation LC50 >200 mg/L - Inhalation Duration=1 hr In Vivo; AcuteInhalNICEATM; Rat Acute Inhalation Toxicity sheet=Data; excel_row=4008; Record_ID=acute_inhalation_3623; Data_Type=In Vivo; Internal_Data_Source=AcuteInhalNICEATM; Mixture=Chemical; DTXSID=DTXSID7027209; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=200; Response_Unit=mg/L; Reference=REACH; URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/5521/7/3/3/?documentUUID=cc014990-20d5-4c10-ad42-23093135aa98; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID7027209
ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669ead96e4b0a7c65d1c4f0e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/18930/7/6/2?documentUUID=e491bb11-2f9e-4a7b-8d80-ff69a43669a2; YEAR=1979; ORIGINAL_YEAR=1979; TOXICOLOGICAL_EFFECT=behaviour (functional findings)|water consumption and compound intake|body weight and weight gain|clinical biochemistry|clinical signs|food consumption and compound intake|gross pathology|haematology|histopathology: non-neoplastic|mortality|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical chemistry|clinical signs|food and/or water consumption|gross pathology|hematology|mortality/survival|neurobehavior|nonneoplastic histopathology|organ weight; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15837595_15848886:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_136e75b4aade081758f08518cf0a2e2a
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =16.4 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15635800:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_5231e235bcfbd18261445def9771403c
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier H92E6QA4FV UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Zn","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H92E6QA4FV"}
openFDA substances FDA UNII substance identifier H92E6QA4FV UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Zn","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H92E6QA4FV"}
openFDA substances FDA UNII substance identifier H92E6QA4FV UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Zn","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H92E6QA4FV"}
openFDA substances FDA UNII substance identifier H92E6QA4FV UNII - - - chemical {"approval_status":null,"molecular_formula":"2C18H35O2.Zn","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"H92E6QA4FV"}