Is Xylose safe in cosmetics?
Xylose has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Xylose
Also known as: (+)-Xylose, 4-01-00-04223, BRN 1562108, EINECS 200-400-7, FEMA No. 3606 (+11 more)
INCI: XYLOSE (D-XYLOSE)
Xylose (CAS 58-86-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent, humectant, flavoring agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 58-86-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent, humectant, flavoring agent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(3R,4S,5R)-oxane-2,3,4,5-tetrol
InChIKey
SRBFZHDQGSBBOR-IOVATXLUSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS for food use; no cosmetic restrictions; well-established safety profile
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Xylose.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Fragrance
Humectant
Softener and conditioner
Regulatory List Membership (2)
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Xylose.
Regulatory Flags
fda_food_additive
Known Synonyms
(+)-Xylose
4-01-00-04223
BRN 1562108
EINECS 200-400-7
FEMA No. 3606
NSC 122762
2,3,4,5-Tetrahydroxypentanal
UNII-A1TA934AKO
(3R,4S,5R)-oxane-2,3,4,5-tetrol
(3R,4S,5R)-tetrahydro-2H-pyran-2,3,4,5-tetrol
D-Xylo-pentose
D-xylopentose
Xylo-pfan
Xylomed
Xyloside
D-xylopyranose
Chemical Function
Humectant
Deodorizer
Softener and conditioner
Flavouring and nutrient
Fragrance
Regulatory Lists
inert_ingredient; Pesticides
inert_ingredient; non_food_use; Pesticides
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
XYLOSE
ChEMBL ID
CHEMBL1236821
Max Phase
4
Frequently Asked Questions
Is Xylose allowed in the EU?
Xylose EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Xylose do in cosmetics?
Xylose functions as: Skin conditioning agent, humectant, flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 58-86-6.
Is Xylose used outside cosmetics?
Xylose also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Xylose compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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