INCI: VITIS VINIFERA (GRAPE) SKIN EXTRACT
Vitis Vinifera Skin Extract (CAS 85594-37-2) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent; colorant; flavoring agent. Reported NOAEL =50 mg/kg bw/d in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted; 3 safety opinions reviewed (cir). Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 85594-37-2 →
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Margin of Safety, dermal absorption, and sensitization profile summaries for Vitis Vinifera Skin Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
10 study endpoints found for Vitis Vinifera Skin Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =50 mg/kg bw/d | oral | rat | inhalation toxicity | CIR_vision_codex |
| NOAEL | =50 mg/kg bw/d | oral | rat | inhalation toxicity | CIR_vision_codex |
| NOAEL | =50 mg/kg bw/d | oral | rat | inhalation toxicity | CIR_vision_codex |
| NOAEL | =50 mg/kg bw/d | oral | rat | inhalation toxicity | CIR_vision_codex |
| NOAEL | =300 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =300 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =300 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =300 mg/kg/d | oral | rat | oral toxicity | CIR_vision_codex |
| NOAEL | =2150 mg/kg bw/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
| NOAEL | =2150 mg/kg bw/d | oral | rat | repeated dose toxicity | CIR_vision_codex |
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
Expert safety assessment and concern-level summary for Vitis Vinifera Skin Extract.
Public NOAEL study rows linked to Vitis Vinifera Skin Extract by CAS number or substance name.
Units vary across source rows: mg/kg/d, mg/kg bw/d
Vitis Vinifera Skin Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Vitis Vinifera Skin Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
Vitis Vinifera Skin Extract functions as: Skin conditioning agent; colorant; flavoring agent. It is classified as a cosmetic ingredient in our database. CAS number: 85594-37-2.
The NOAEL (No Observed Adverse Effect Level) for Vitis Vinifera Skin Extract is =50 mg/kg bw/d based on a inhalation toxicity study via oral route in rat. A total of 10 study endpoints are available. Source: CIR_vision_codex.
Check Vitis Vinifera Skin Extract compliance across multiple jurisdictions:
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Vitis Vinifera Skin Extract in your formulation.