Is Urease safe in cosmetics?
Urease has a safety rating of "GOOD" in our database. EU status: restricted. US status: prohibited.
Good
Cosmetic Ingredient
Urease
Also known as: EINECS 232-656-0, Jack bean urease
INCI: UREASE
Urease (CAS 9002-13-5) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent (enzyme that hydrolyzes urea to ammonia and CO₂). EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 9002-13-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent (enzyme that hydrolyzes urea to ammonia and CO₂)
Safety Rating
GOOD
Regulatory Status
EU EU Status
restricted
US US Status
prohibited
US Notes
Permitted for cosmetic use; not listed as prohibited or restricted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Urease.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for Urease.
Known Synonyms
EINECS 232-656-0
Jack bean urease
Chemical Function
Viscosity modifier
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Urease allowed in the EU?
Urease EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Urease do in cosmetics?
Urease functions as: Skin conditioning agent (enzyme that hydrolyzes urea to ammonia and CO₂). It is classified as a cosmetic ingredient in our database. CAS number: 9002-13-5.
Compliance Tools
Check Urease compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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