NOAEL Studies Cosmetic Ingredient

Tricyclodecenyl Propionate NOAEL Studies

INCI: TRICYCLODECENYL PROPIONATE

CAS: 17511-60-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 >5000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_3394; row=14289; data_type=In Vivo; mixture=Chemical; chemical_name=4,7-Methano-1H-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-, propanoate; preferred_name=4,7-Methano-1H-inden-6-ol, 3a,4,5,6,7,7a-hexahydro-, propanoate; dtxsid=DTXSID8036312; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8036312; source_file=acute_oral.xlsx
NTP_ICE_skin_sensitization 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_skin_sensitization Incidence of positive responses 0 % Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=5810; Record_ID=skin_sensitization_invivo_1340; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=20.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8036312; Assay=Human Maximization Test; Endpoint=Incidence of positive responses; Response=0; Response_Unit=%; Species=Human; Route=Dermal; Reference=Kligman 1976: report to RIFM|RIFM 1976; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Anonymous 1979; Not available; 10.1016/S0015-6264(79)80095-4; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8036312
NTP_ICE_skin_sensitization Induction dose per skin area 13500 ug/cm2 Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=5808; Record_ID=skin_sensitization_invivo_1340; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=20.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8036312; Assay=Human Maximization Test; Endpoint=Induction dose per skin area; Response=13500; Response_Unit=ug/cm2; Species=Human; Route=Dermal; Reference=Kligman 1976: report to RIFM|RIFM 1976; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Anonymous 1979; Not available; 10.1016/S0015-6264(79)80095-4; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8036312
NTP_ICE_skin_sensitization Relative reliability score 3 unitless Human Dermal - In Vivo; HPPT2020WIP; Human Maximization Test sheet=Data_invivo; excel_row=5814; Record_ID=skin_sensitization_invivo_1340; Data_Type=In Vivo; Internal_Data_Source=HPPT2020WIP; Concentration=20.0; Concentration_Units=%; Mixture=Chemical; DTXSID=DTXSID8036312; Assay=Human Maximization Test; Endpoint=Relative reliability score; Response=3; Response_Unit=Unitless; Species=Human; Route=Dermal; Reference=Kligman 1976: report to RIFM|RIFM 1976; https://www.rifm.org/rifm-science-database.php#gsc.tab=0|Anonymous 1979; Not available; 10.1016/S0015-6264(79)80095-4; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID8036312
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier S3ASM14UAS UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H18O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"S3ASM14UAS"}
openFDA substances FDA UNII substance identifier S3ASM14UAS UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H18O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"S3ASM14UAS"}
openFDA substances FDA UNII substance identifier S3ASM14UAS UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H18O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"S3ASM14UAS"}
openFDA substances FDA UNII substance identifier S3ASM14UAS UNII - - - chemical {"approval_status":null,"molecular_formula":"C13H18O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"S3ASM14UAS"}