NOAEL Studies Cosmetic Ingredient

Thymol NOAEL Studies

INCI: THYMOL

CAS: 89-83-8

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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COSMOS_DB 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
COSMOS_DB NOAEL 1000 mg/kg bw/day rat oral 113 day Subchronic US FDA CFSAN PAFA; US FDA CFSAN PAFA Study
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip 27 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 667 mg/kg bw/day rat oral: feed - toxicity to reproduction: other studies dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=74353b82-79cf-413f-8f12-20e7dc789619_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=74353b82-79cf-413f-8f12-20e7dc789619/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproductionOther; literature=Name=Unnamed; ReferenceYear=1967; basis=other:; key_result=false; entry_uuid=c2f41b3f-792a-4c31-acdb-a2b78d91c685
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 0.42 mg/kg bw/day mouse inhalation: aerosol - sub-chronic toxicity: inhalation dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=bd7a4cfd-1bae-47c0-a507-ce5bf4d87393_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=bd7a4cfd-1bae-47c0-a507-ce5bf4d87393/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityInhalation; literature=Name=Unnamed; ReferenceYear=2019; key_result=false; entry_uuid=636a18db-759e-49b7-9e6c-e01d32f99b22
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 250 mg/kg bw/day mouse intraperitoneal - carcinogenicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=c0147b45-5103-4491-bb42-1daeaa2b00fb_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=c0147b45-5103-4491-bb42-1daeaa2b00fb/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=Carcinogenicity; literature=Name=Unnamed; ReferenceYear=1973; basis=other:; key_result=false; entry_uuid=3723cbed-8655-46d5-9665-4d4aa7a6677b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 40 mg/kg bw/day rat oral: gavage - screening for reproductive / developmental toxicity dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=57f05200-80ac-4870-8fff-3beabbfe295c_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=57f05200-80ac-4870-8fff-3beabbfe295c/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2010; basis=viability; key_result=false; entry_uuid=3c55652e-60f4-45b3-a780-68b923d2aedf
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 500 mg/kg bw/day rat oral: feed - reproductive toxicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=80f7f6f4-61cf-4908-bcd5-f0d1eb22b8fa_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=80f7f6f4-61cf-4908-bcd5-f0d1eb22b8fa/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1967; basis=clinical signs; key_result=false; entry_uuid=54e61dfb-0c91-4f15-a67a-80574c1ef40f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 299 mg/kg bw/day rabbit oral: capsule - reproductive toxicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=e5d7533a-1d36-47a5-aadb-a3c44e8e3c5f_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=e5d7533a-1d36-47a5-aadb-a3c44e8e3c5f/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1985; basis=mortality; key_result=false; entry_uuid=3f958b66-b307-4cef-af29-b32862183e20
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 61.55 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=8492f812-42dd-4e29-b6e1-c0b880a0b483_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=8492f812-42dd-4e29-b6e1-c0b880a0b483/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2012; key_result=false; entry_uuid=fc4cc3d8-5951-4da3-837d-6e3f454f475e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 667 mg/kg bw/day rat oral: feed - toxicity to reproduction: other studies dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=74353b82-79cf-413f-8f12-20e7dc789619_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=74353b82-79cf-413f-8f12-20e7dc789619/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproductionOther; literature=Name=Unnamed; ReferenceYear=1967; basis=other:; key_result=false; entry_uuid=c2f41b3f-792a-4c31-acdb-a2b78d91c685
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 0.42 mg/kg bw/day mouse inhalation: aerosol - sub-chronic toxicity: inhalation dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=bd7a4cfd-1bae-47c0-a507-ce5bf4d87393_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=bd7a4cfd-1bae-47c0-a507-ce5bf4d87393/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityInhalation; literature=Name=Unnamed; ReferenceYear=2019; key_result=false; entry_uuid=636a18db-759e-49b7-9e6c-e01d32f99b22
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 250 mg/kg bw/day mouse intraperitoneal - carcinogenicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=c0147b45-5103-4491-bb42-1daeaa2b00fb_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=c0147b45-5103-4491-bb42-1daeaa2b00fb/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=Carcinogenicity; literature=Name=Unnamed; ReferenceYear=1973; basis=other:; key_result=false; entry_uuid=3723cbed-8655-46d5-9665-4d4aa7a6677b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 40 mg/kg bw/day rat oral: gavage - screening for reproductive / developmental toxicity dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=57f05200-80ac-4870-8fff-3beabbfe295c_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=57f05200-80ac-4870-8fff-3beabbfe295c/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2010; basis=viability; key_result=false; entry_uuid=3c55652e-60f4-45b3-a780-68b923d2aedf
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 500 mg/kg bw/day rat oral: feed - reproductive toxicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=80f7f6f4-61cf-4908-bcd5-f0d1eb22b8fa_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=80f7f6f4-61cf-4908-bcd5-f0d1eb22b8fa/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1967; basis=clinical signs; key_result=false; entry_uuid=54e61dfb-0c91-4f15-a67a-80574c1ef40f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 299 mg/kg bw/day rabbit oral: capsule - reproductive toxicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=e5d7533a-1d36-47a5-aadb-a3c44e8e3c5f_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=e5d7533a-1d36-47a5-aadb-a3c44e8e3c5f/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1985; basis=mortality; key_result=false; entry_uuid=3f958b66-b307-4cef-af29-b32862183e20
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 61.55 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=8492f812-42dd-4e29-b6e1-c0b880a0b483_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=8492f812-42dd-4e29-b6e1-c0b880a0b483/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2012; key_result=false; entry_uuid=fc4cc3d8-5951-4da3-837d-6e3f454f475e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 667 mg/kg bw/day rat oral: feed - toxicity to reproduction: other studies dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=74353b82-79cf-413f-8f12-20e7dc789619_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=74353b82-79cf-413f-8f12-20e7dc789619/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproductionOther; literature=Name=Unnamed; ReferenceYear=1967; basis=other:; key_result=false; entry_uuid=c2f41b3f-792a-4c31-acdb-a2b78d91c685
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 0.42 mg/kg bw/day mouse inhalation: aerosol - sub-chronic toxicity: inhalation dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=bd7a4cfd-1bae-47c0-a507-ce5bf4d87393_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=bd7a4cfd-1bae-47c0-a507-ce5bf4d87393/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityInhalation; literature=Name=Unnamed; ReferenceYear=2019; key_result=false; entry_uuid=636a18db-759e-49b7-9e6c-e01d32f99b22
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 250 mg/kg bw/day mouse intraperitoneal - carcinogenicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=c0147b45-5103-4491-bb42-1daeaa2b00fb_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=c0147b45-5103-4491-bb42-1daeaa2b00fb/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=Carcinogenicity; literature=Name=Unnamed; ReferenceYear=1973; basis=other:; key_result=false; entry_uuid=3723cbed-8655-46d5-9665-4d4aa7a6677b
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 40 mg/kg bw/day rat oral: gavage - screening for reproductive / developmental toxicity dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=57f05200-80ac-4870-8fff-3beabbfe295c_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=57f05200-80ac-4870-8fff-3beabbfe295c/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=2010; basis=viability; key_result=false; entry_uuid=3c55652e-60f4-45b3-a780-68b923d2aedf
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 500 mg/kg bw/day rat oral: feed - reproductive toxicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=80f7f6f4-61cf-4908-bcd5-f0d1eb22b8fa_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=80f7f6f4-61cf-4908-bcd5-f0d1eb22b8fa/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1967; basis=clinical signs; key_result=false; entry_uuid=54e61dfb-0c91-4f15-a67a-80574c1ef40f
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 299 mg/kg bw/day rabbit oral: capsule - reproductive toxicity, other dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=e5d7533a-1d36-47a5-aadb-a3c44e8e3c5f_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=e5d7533a-1d36-47a5-aadb-a3c44e8e3c5f/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1985; basis=mortality; key_result=false; entry_uuid=3f958b66-b307-4cef-af29-b32862183e20
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOAEL 61.55 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=8492f812-42dd-4e29-b6e1-c0b880a0b483_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=8492f812-42dd-4e29-b6e1-c0b880a0b483/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=2012; key_result=false; entry_uuid=fc4cc3d8-5951-4da3-837d-6e3f454f475e
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL 200 mg/kg bw/day rat oral: gavage - screening for reproductive / developmental toxicity dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=afdfefe1-e483-4536-9bd3-c7324cbffaa4_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=afdfefe1-e483-4536-9bd3-c7324cbffaa4/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1996; basis=reproductive performance; key_result=true; entry_uuid=ffb45000-db44-40b4-b3da-5f96bf7c1815
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL 8 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=aac9d3ec-6e09-4fdd-a53a-cb81ca233d39_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=aac9d3ec-6e09-4fdd-a53a-cb81ca233d39/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1996; basis=histopathology: non-neoplastic; key_result=false; entry_uuid=e4a6dcbc-9cc0-43f5-8886-1df43fa995b3
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL 200 mg/kg bw/day rat oral: gavage - screening for reproductive / developmental toxicity dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=afdfefe1-e483-4536-9bd3-c7324cbffaa4_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=afdfefe1-e483-4536-9bd3-c7324cbffaa4/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1996; basis=reproductive performance; key_result=true; entry_uuid=ffb45000-db44-40b4-b3da-5f96bf7c1815
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL 8 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=aac9d3ec-6e09-4fdd-a53a-cb81ca233d39_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=aac9d3ec-6e09-4fdd-a53a-cb81ca233d39/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1996; basis=histopathology: non-neoplastic; key_result=false; entry_uuid=e4a6dcbc-9cc0-43f5-8886-1df43fa995b3
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL 200 mg/kg bw/day rat oral: gavage - screening for reproductive / developmental toxicity dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=afdfefe1-e483-4536-9bd3-c7324cbffaa4_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=afdfefe1-e483-4536-9bd3-c7324cbffaa4/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=ToxicityReproduction; literature=Name=Unnamed; ReferenceYear=1996; basis=reproductive performance; key_result=true; entry_uuid=ffb45000-db44-40b4-b3da-5f96bf7c1815
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip NOEL 8 mg/kg bw/day rat oral: gavage - short-term repeated dose toxicity: oral dossier=ff53feae-f288-484c-8bf1-98076732bc4c.i6z; document=aac9d3ec-6e09-4fdd-a53a-cb81ca233d39_ff53feae-f288-484c-8bf1-98076732bc4c.i6d; document_key=aac9d3ec-6e09-4fdd-a53a-cb81ca233d39/ff53feae-f288-484c-8bf1-98076732bc4c; document_subtype=RepeatedDoseToxicityOral; literature=Name=Unnamed; ReferenceYear=1996; basis=histopathology: non-neoplastic; key_result=false; entry_uuid=e4a6dcbc-9cc0-43f5-8886-1df43fa995b3
NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =980 mg/kg bw Rat (Male/Female) oral acute Rat Acute Oral Toxicity Pesticide Active Ingredients Database (undated); record_id=acute_oral_11185; row=10757; data_type=In Vivo; mixture=Chemical; chemical_name=Thymol; preferred_name=Thymol; dtxsid=DTXSID6034972; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6034972; source_file=acute_oral.xlsx
NTP_ICE_endocrine 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_endocrine AC50 34.8793541035235 uM - - - ERPathway2016; ER Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=15518; RecordID=ERPathway2016_448; DatasetName=ERPathway2016; DTXSID=DTXSID6034972; Assay=ER Pathway Model, Antagonist; Endpoint=AC50; Response=34.8793541035235; Response_Unit=uM; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6034972
NTP_ICE_endocrine ACC 32.4473838912271 uM - - - ERPathway2016; ER Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=15519; RecordID=ERPathway2016_448; DatasetName=ERPathway2016; DTXSID=DTXSID6034972; Assay=ER Pathway Model, Antagonist; Endpoint=ACC; Response=32.4473838912271; Response_Unit=uM; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6034972
NTP_ICE_endocrine Model Score 0 unitless - - - ARPathway2016; AR Pathway Model, Antagonist sheet=Integrated_approaches; excel_row=15514; RecordID=ARPathway2016_1690; DatasetName=ARPathway2016; DTXSID=DTXSID6034972; Assay=AR Pathway Model, Antagonist; Endpoint=Model Score; Response=0; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6034972
NTP_ICE_endocrine Model Score 0.00465 unitless - - - ERPathway2016; ER Pathway Model, Agonist sheet=Integrated_approaches; excel_row=15520; RecordID=ERPathway2016_448; DatasetName=ERPathway2016; DTXSID=DTXSID6034972; Assay=ER Pathway Model, Agonist; Endpoint=Model Score; Response=0.00465; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6034972
ToxValDB_ECOTOX 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECOTOX LOEL =0.1 mmol Rat injection acute; 0.0938 days acute LONG_REF=Biochem. J. (Lond.)50:473-479 Arnott,D.G., and I. Doniach The Effect of Compounds Allied to Resorcinol upon the Uptake of Radioactive Iodine (131I) by the Thyroid of the Rat 1952; TITLE=The Effect of Compounds Allied to Resorcinol upon the Uptake of Radioactive Iodine (131I) by the Thyroid of the Rat; AUTHOR=Arnott,D.G., and I. Doniach; DOI=10.1042/bj0500473; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=97800; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1952; ORIGINAL_YEAR=1952; TOXICOLOGICAL_EFFECT=Physiology: Iodine uptake; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15596485:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=c47d37a64f9c0d598c80b4069f036268
ToxValDB_ECOTOX NOEL =0.25 mmol Rat injection acute; 0.0833 days acute LONG_REF=Biochem. J. (Lond.)50:473-479 Arnott,D.G., and I. Doniach The Effect of Compounds Allied to Resorcinol upon the Uptake of Radioactive Iodine (131I) by the Thyroid of the Rat 1952; TITLE=The Effect of Compounds Allied to Resorcinol upon the Uptake of Radioactive Iodine (131I) by the Thyroid of the Rat; AUTHOR=Arnott,D.G., and I. Doniach; DOI=10.1042/bj0500473; QUALITY=Control type: Carrier or solvent control; EXTERNAL_SOURCE_ID=97800; EXTERNAL_SOURCE_ID_DESC=ECOTOX Reference Number; STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6759bce8e4b0a7c65d37bc5f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://cfpub.epa.gov/ecotox/; YEAR=1952; ORIGINAL_YEAR=1952; TOXICOLOGICAL_EFFECT=Physiology: Iodine uptake; TOXICOLOGICAL_EFFECT_CATEGORY=other; STUDY_GROUP=ECOTOX:15606526:F:--; QC_CATEGORY=Data source QC'd by data provider prior to ECOTOX import; QC_STATUS=not determined; SOURCE_HASH=75434eca67c2202511fe82b8684302aa
ToxValDB_GESTIS_DNEL 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =32.9 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15635246_15635247:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_52c7d1efabdc2993f1a9059301ab897d
ToxValDB_GESTIS_DNEL DNEL systemic =49.3 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15635246_15635247:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_71fb867e1a732b7653daa589cf009925
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 3J50XA376E UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3J50XA376E"}
openFDA substances FDA UNII substance identifier 3J50XA376E UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3J50XA376E"}
openFDA substances FDA UNII substance identifier 3J50XA376E UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3J50XA376E"}
openFDA substances FDA UNII substance identifier 3J50XA376E UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H14O","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"3J50XA376E"}