Is Thianthol safe in cosmetics?
Thianthol has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Thianthol
Also known as: 2,7-Dimethylthianthrene, EINECS 205-202-4, Mesulphen, Thiantholum, Mitigal (+6 more)
INCI: THIANTHOL
Thianthol (CAS 135-58-0) is a cosmetic cosmetic ingredient functioning as Antimicrobial, deodorant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 135-58-0 →
Auto-generated CPSR Part A draft with source citations
Function
Antimicrobial, deodorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
2,7-dimethylthianthrene
InChIKey
AHXDSVSZEZHDLV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Thianthol.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Thianthol.
Known Synonyms
2,7-Dimethylthianthrene
EINECS 205-202-4
Mesulphen
Thiantholum
Mitigal
Soufrol
Thiotal
Mesulfene
Mesulfeno
Mesulfenum
UNII-EG6V6W7WDD
Chemical Function
Biocide
Softener and conditioner
Regulatory Lists
pharmaceutical
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
MESULFEN
ChEMBL ID
CHEMBL2106968
Max Phase
2
Frequently Asked Questions
Is Thianthol allowed in the EU?
Thianthol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Thianthol do in cosmetics?
Thianthol functions as: Antimicrobial, deodorant. It is classified as a cosmetic ingredient in our database. CAS number: 135-58-0.
Is Thianthol used outside cosmetics?
Thianthol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Thianthol compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acrylates/Vinyl Neodecanoate Crosspolymer
Excellent
Same category
Emulsion stabilising, film forming
Adipic Acid
Excellent
Same category
Buffering
Aluminum Magnesium Oxide
Excellent
Same category
Absorbent, bulking agent, opacifying ...
Ammonium VA/Acrylates Copolymer
Excellent
Same category
Antistatic, binding, film forming, ha...
Ammonium VA/Crotonic Acid Copolymer
Excellent
Same category
Antistatic, film forming, hair fixing...
Aphanothece Sacrum Polysaccharide
Excellent
Same category
Absorbent, emulsion stabilising, film...
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
2-NAPHTHOL
Moderate
Chemical family
Hair Dyeing, Perfuming
2-Naphthol (β-Naphthol) 🔴
Poor
Chemical family
Historically used as hair dye coupler...
Disodium Hydroxyethyliminodiacetate
Poor
Chemical family
Chelating agent (HEIDA salt — structu...
Is Thianthol in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Thianthol in your formulation.