Is Tetrahydrodemethoxydiferuloylmethane safe in cosmetics?
Tetrahydrodemethoxydiferuloylmethane has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Tetrahydrodemethoxydiferuloylmethane
Also known as: UNII-44D8X9U00T, 3,5-Heptanedione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-, Demethoxytetrahydrocurcumin, Tetrahydrodemethoxycurcumin
INCI: TETRAHYDRODEMETHOXYDIFERULOYLMETHANE
Tetrahydrodemethoxydiferuloylmethane (CAS 149579-07-7) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin conditioning, Skin brightening. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 149579-07-7 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin conditioning, Skin brightening
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-dione
InChIKey
HJFYFYWETUVIHT-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrahydrodemethoxydiferuloylmethane.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Tetrahydrodemethoxydiferuloylmethane.
Known Synonyms
UNII-44D8X9U00T
3,5-Heptanedione, 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-
Demethoxytetrahydrocurcumin
Tetrahydrodemethoxycurcumin
Chemical Function
Antioxidant
Softener and conditioner
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
TETRAHYDRODEMETHOXYCURCUMIN
ChEMBL ID
CHEMBL1087639
Frequently Asked Questions
Is Tetrahydrodemethoxydiferuloylmethane allowed in the EU?
Tetrahydrodemethoxydiferuloylmethane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrahydrodemethoxydiferuloylmethane do in cosmetics?
Tetrahydrodemethoxydiferuloylmethane functions as: Antioxidant, Skin conditioning, Skin brightening. It is classified as a cosmetic ingredient in our database. CAS number: 149579-07-7.
Is Tetrahydrodemethoxydiferuloylmethane used outside cosmetics?
Tetrahydrodemethoxydiferuloylmethane also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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