Is Tetraacetylphytosphingosine safe in cosmetics?
Tetraacetylphytosphingosine has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Tetraacetylphytosphingosine
Also known as: UNII-S6T795QLF2, Acetamide, N-((1S,2S,3R)-2,3-bis(acetyloxy)-1-((acetyloxy)methyl)heptadecyl)-, Acetamide, N-(2,3-bis(acetyloxy)-1-((acetyloxy)methyl)heptadecyl)-, (1S-(1R*,2R*,3S*))-, Acetamide, N-(2,3-dihydroxy-1-(hydroxymethyl)heptadecyl)-, triacetate (ester), d-ribo-, Biomide taps (+5 more)
INCI: TETRAACETYLPHYTOSPHINGOSINE
Tetraacetylphytosphingosine (CAS 13018-48-9) is a cosmetic cosmetic ingredient functioning as Skin conditioning, hair conditioning, ceramide precursor (barrier repair,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 13018-48-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Tetraacetylphytosphingosine is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin conditioning, hair conditioning, ceramide precursor (barrier repair, anti-aging, moisturizing)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
[(2S,3S,4R)-2-acetamido-3,4-diacetyloxyoctadecyl] acetate
InChIKey
SGTYQWGEVAMVKB-NXCFDTQHSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; not restricted
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetraacetylphytosphingosine.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Tetraacetylphytosphingosine.
Known Synonyms
UNII-S6T795QLF2
Acetamide, N-((1S,2S,3R)-2,3-bis(acetyloxy)-1-((acetyloxy)methyl)heptadecyl)-
Acetamide, N-(2,3-bis(acetyloxy)-1-((acetyloxy)methyl)heptadecyl)-, (1S-(1R*,2R*,3S*))-
Acetamide, N-(2,3-dihydroxy-1-(hydroxymethyl)heptadecyl)-, triacetate (ester), d-ribo-
Biomide taps
Cytomide taps
D-Ribo-1,3,4-triacetoxy-2-acetamidooctadecane
DS-Taps
Tetraacetyl-4-hydroxysphinganine
Tetraacetylphytospingosine
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Tetraacetylphytosphingosine allowed in the EU?
Tetraacetylphytosphingosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetraacetylphytosphingosine do in cosmetics?
Tetraacetylphytosphingosine functions as: Skin conditioning, hair conditioning, ceramide precursor (barrier repair, anti-aging, moisturizing). It is classified as a cosmetic ingredient in our database. CAS number: 13018-48-9.
Is Tetraacetylphytosphingosine used outside cosmetics?
Tetraacetylphytosphingosine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Tetraacetylphytosphingosine have different safety status in cosmetics vs industrial chemicals?
Tetraacetylphytosphingosine is classified GHS Danger (H318, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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