Is Teprenone safe in cosmetics?
Teprenone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Teprenone
Also known as: Teprenona, Teprenonum, UNII-S8S8451A4O, Geranylgeranylacetone
INCI: TEPRENONE (GERANYLGERANONE / GGA); TYPICALLY SUPPLIED AS CAPRYLIC/CAPRIC TRIGLYCERIDE \& TEPRENONE
Teprenone (CAS 6809-52-5) is a cosmetic cosmetic ingredient functioning as Skin Conditioning; anti-aging (telomere protection, cellular senescence. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 6809-52-5 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning; anti-aging (telomere protection, cellular senescence reduction)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(5E,9E,13E)-6,10,14,18-tetramethylnonadeca-5,9,13,17-tetraen-2-one
InChIKey
HUCXKZBETONXFO-NJFMWZAGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use; no specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Teprenone.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Teprenone.
Known Synonyms
Teprenona
Teprenonum
UNII-S8S8451A4O
Geranylgeranylacetone
Chemical Function
Softener and conditioner
Regulatory Lists
pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183658
Adverse Event Associations
164
Frequently Asked Questions
Is Teprenone allowed in the EU?
Teprenone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Teprenone do in cosmetics?
Teprenone functions as: Skin Conditioning; anti-aging (telomere protection, cellular senescence reduction). It is classified as a cosmetic ingredient in our database. CAS number: 6809-52-5.
Is Teprenone used outside cosmetics?
Teprenone also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Teprenone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Same category
Skin conditioning (skin brightening/l...
4-Amino-3-Hydroxybutyric Acid
Excellent
Same category
Skin Conditioning
Acetyl Glycyl Beta-Alanine
Excellent
Same category
Skin conditioning agent with melanin ...
Acetyl Tripeptide-1
Excellent
Same category
Skin Conditioning
Acetylneuraminic Acid
Excellent
Same category
Skin Conditioning, Skin Protecting
Acetylphytosphingosine
Excellent
Same category
Skin Conditioning, Hair Conditioning;...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good
Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good
Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good
Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good
Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good
Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good
Similar safety
Antioxidant
TEREPHTHALIC ACID/ISOPHTHALIC ACID/SODIUM ISOPHTHALIC ACID SULFONATE/GLYCOL COPOLYMER
Good
Browse nearby
Film Forming, Hair Fixing
TERMINALIA ARJUNA BARK EXTRACT
Good
Browse nearby
Skin Conditioning
TERMINALIA CHEBULA EXTRACT
Good
Browse nearby
Astringent, Skin Conditioning
Is Teprenone in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Teprenone in your formulation.