NOAEL Studies
Cosmetic Ingredient
Sunfloweramide MEA NOAEL Studies
INCI: SUNFLOWERAMIDE MEA
CAS: 69227-24-3
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ToxValDB_ECHA_IUCLID 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | LEL | ~1000 | mg/kg bw/day | Rat | oral | short-term; 2 weeks | short-term | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7ca27e4b0a7c65d2209c1; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15928/7/6/2?documentUUID=316af4ce-fbb8-4f1a-b826-8916103a82a2; YEAR=1967; ORIGINAL_YEAR=1967; TOXICOLOGICAL_EFFECT=body weight and weight gain|clinical signs|food consumption and compound intake|gross pathology|mortality|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|food and/or water consumption|gross pathology|mortality/survival|organ weight; STUDY_GROUP=ECHA IUCLID:15831747:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_3698f6ded40b85bbd4489d079ae352c6 |
| ToxValDB_ECHA_IUCLID | NOAEL | =1000 | mg/kg bw/day | Rat | oral | subchronic; 63 days | subchronic | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cc0be4b0a7c65d228a32; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15928/7/6/2?documentUUID=316af4ce-fbb8-4f1a-b826-8916103a82a2; YEAR=1967; ORIGINAL_YEAR=1967; TOXICOLOGICAL_EFFECT=behaviour (functional findings)|urinalysis|water consumption and compound intake|other endocrine activity endpoints|body weight and weight gain|clinical signs|food consumption and compound intake|gross pathology|haematology|histopathology: non-neoplastic|mortality|neuropathology|sperm measures; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical signs|food and/or water consumption|gross pathology|hematology|mortality/survival|neurobehavior|nonneoplastic histopathology|other|reproduction|urinalysis; STUDY_GROUP=ECHA IUCLID:15832663:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c091aa00a08966048867de81d79001fa |
ToxValDB_GESTIS_DNEL 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =73.4 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15629664_15629665:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2641af219cd9855ddc36a5bba889ec8c |
| ToxValDB_GESTIS_DNEL | DNEL systemic | =16.4 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL_dup_-_15629664_15629665:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0767d70961cb4a34e07f67883f6b0b1d |
openFDA substances 8 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | K2H84XNW3Y | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"K2H84XNW3Y"} |
| openFDA substances | FDA UNII substance identifier | 3VVG2UI23S | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"3VVG2UI23S"} |
| openFDA substances | FDA UNII substance identifier | K2H84XNW3Y | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"K2H84XNW3Y"} |
| openFDA substances | FDA UNII substance identifier | K2H84XNW3Y | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"K2H84XNW3Y"} |
| openFDA substances | FDA UNII substance identifier | 3VVG2UI23S | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"3VVG2UI23S"} |
| openFDA substances | FDA UNII substance identifier | 3VVG2UI23S | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"3VVG2UI23S"} |
| openFDA substances | FDA UNII substance identifier | K2H84XNW3Y | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"K2H84XNW3Y"} |
| openFDA substances | FDA UNII substance identifier | 3VVG2UI23S | UNII | - | - | - | mixture | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"mixture","unii_code":"3VVG2UI23S"} |