Good Cosmetic Ingredient Sensitization Data

Stearamidopropyl Dimethylamine

Also known as: Octadecanamide, N-[3-(dimethylamino)propyl]-, N,N-Dimethyl-3-octadecanoylaminopropylamine, N,N-Dimethyl-N-(3-stearamidopropyl)amine, EINECS 231-609-1, UNII-K7VEI00UFR

INCI: STEARAMIDOPROPYL DIMETHYLAMINE

Stearamidopropyl Dimethylamine (CAS 7651-02-7) is a cosmetic cosmetic ingredient functioning as Antistatic, Emulsifying, Hair Conditioning, Surfactant. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 7651-02-7 →

Auto-generated CPSR Part A draft with source citations
Function
Antistatic, Emulsifying, Hair Conditioning, Surfactant
Safety Rating
GOOD

Chemistry & Identifiers

Formula
C23H48N2O
MW
368.6 g/mol
EC Number
231-609-1
PubChem CID
62109
IUPAC Name
N-[3-(dimethylamino)propyl]octadecanamide
InChIKey
WWVIUVHFPSALDO-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR reviewed (2014) — safe when formulated to be non-sensitizing

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Stearamidopropyl Dimethylamine.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Stearamidopropyl Dimethylamine based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
surfactant
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
amidoamine-group
Reaction Type
contact-dermatitis

Source: NACDG; IVDK; ESSCA

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Additional Ingredient Properties

5 property records from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "surfactant", "cross_reactivity_group": "amidoamine-group", "patch_test_frequency_pct": "0.3", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "NACDG; IVDK; ESSCA"}
emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "o_w", "critical_packing_parameter": "0.30-0.45", "emulsion_stabilization_mechanism": "electrostatic_steric", "co_emulsifier_pairs": "cetearyl_alcohol,lactic_acid", "optimal_oil_phase_pct": "10-28", "optimal_water_phase_pct": "72-90", "electrolyte_tolerance": "low", "pH_emulsion_stability_range": "3.0-6.5", "viscosity_building_contribution":…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "medium/coarse", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutr…
hair_conditioning
{"cas_number": "7651-02-7", "ingredient_class": "cationic_conditioner", "chemical_type": "quaternary_ammonium", "charge_density_meq_g": "medium", "substantivity_to_hair": "good", "deposition_from_shampoo": "no", "deposition_from_conditioner": "yes", "conditioning_mechanism": "electrostatic", "hair_penetration": "cuticle", "molecular_weight_effect_on_penetration": "medium_chain", "wet_combing_force…
surfactant
{"cas_number": "33105-49-9", "surfactant_type": "amphoteric", "chemical_class": "betaine", "charge_at_use_ph": "zwitterionic", "cmc_critical_micelle_concentration_mm": "0.07218050837455381", "hlb_value": "13.0", "foam_volume_ml_ross_miles": "136", "foam_quality": "creamy", "foam_stability_5min_pct": "82", "cleansing_power_rating_1_to_10": "7.179952430470751", "oil_emulsification_capacity": "good",…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-static agent Emulsifier Softener and conditioner Surfactant (surface active agent)
Regulatory List Membership (1)
EU Regulated in Personal Care

Expert Verdict

Expert safety assessment and concern-level summary for Stearamidopropyl Dimethylamine.

Regulatory Flags

potential-allergen

Known Synonyms

Octadecanamide, N-[3-(dimethylamino)propyl]- N,N-Dimethyl-3-octadecanoylaminopropylamine N,N-Dimethyl-N-(3-stearamidopropyl)amine EINECS 231-609-1 UNII-K7VEI00UFR

Chemical Function

Softener and conditioner Surfactant (surface active agent) Anti-static agent Emulsifier

Regulatory Lists

Europe; Personal care Europe; Personal care

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Stearamidopropyl Dimethylamine safe in cosmetics?

Stearamidopropyl Dimethylamine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Stearamidopropyl Dimethylamine allowed in the EU?

Stearamidopropyl Dimethylamine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Stearamidopropyl Dimethylamine do in cosmetics?

Stearamidopropyl Dimethylamine functions as: Antistatic, Emulsifying, Hair Conditioning, Surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 7651-02-7.

Is Stearamidopropyl Dimethylamine used outside cosmetics?

Stearamidopropyl Dimethylamine also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Stearamidopropyl Dimethylamine have different safety status in cosmetics vs industrial chemicals?

Stearamidopropyl Dimethylamine is classified GHS Danger (H314, H315, H318, H400, H410, H411, H302, H317) in the chemicals database but is allowed in EU cosmetics.

Related Ingredients

Alpha-Glucan Oligosaccharide-1
Excellent Same category
Skin conditioning, cleansing, smoothi...
Ammonium Acryloyl Dimethyltaurate/Carboxyethyl Acrylate Crosspolymer
Excellent Same category
Dispersing agent (nonsurfactant), vis...
Ammonium Cocoyl Isethionate
Excellent Same category
Surfactant – cleansing, foaming
Ammonium Lauryl Sulfosuccinate
Excellent Same category
Cleansing, foaming, surfactant
Ammonium Stearate
Excellent Same category
Cleansing, surfactant, emulsifying
Apricot Kernel Oil Polyglyceryl-10 Esters
Excellent Same category
Skin conditioning, emollient, surfact...
(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
Good Similar safety
Anti-sebum, Antioxidant, Skin Protecting
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
Good Similar safety
Skin Conditioning, Skin Conditioning ...
(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
Good Similar safety
(ANGELICA GIGAS/GLYCYRRHIZA URALENSIS/REHMANNIA GLUTINOSA ROOT)/ANGELICA GIGAS STEM/CARTHAMUS TINCTORIUS FLOWER/(CARTHAMUS TINCTORIUS/PRUNUS PERSICA SEED)PORIA COCOS WATER
Good Similar safety
Humectant, Skin Conditioning, Skin Pr...
(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
Good Similar safety
Anti-seborrheic, Anti-sebum, Antioxid...
(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
Good Similar safety
Antioxidant
Pentasodium Ethylenediamine Tetramethylene Phosphonate
Moderate Chemical family
Chelating agent; viscosity controlling
stearamidopropyl-dimethylamine-safety
Good Chemical family
Surfactant
STEARAMIDE MEA
Good Browse nearby
Antistatic, Surfactant - Foam Boostin...

Is Stearamidopropyl Dimethylamine in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Stearamidopropyl Dimethylamine in your formulation.