Is Soyamidopropylamine Oxide safe in cosmetics?
Soyamidopropylamine Oxide has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Soyamidopropylamine Oxide
Also known as: Alkyldimethylamine oxides, C12-18-alkyldimethyl, C12-C18 alkyl dimethyl amine oxide, Amine oxides, C12-18-alkyldimethyl, Aromox DMB-W, C12-18-alkyldimethyl amine N-oxides (+7 more)
INCI: SOYAMIDOPROPYLAMINE OXIDE
Soyamidopropylamine Oxide (CAS 68955-55-5) is a cosmetic cosmetic ingredient functioning as Surfactant (cleansing/foam boosting), antistatic, hair conditioning. Reported NOAEL =40 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 68955-55-5 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Soyamidopropylamine Oxide is classified GHS Danger (H302, H315, H318, H400, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Surfactant (cleansing/foam boosting), antistatic, hair conditioning
Safety Rating
GOOD
Chemistry & Identifiers
EC Number
931-341-1
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Soyamidopropylamine Oxide.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Soyamidopropylamine Oxide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =40 mg/kg bw/day | oral | Rat | subchronic | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Emulsifier
Fragrance
Surfactant (surface active agent)
Regulatory List Membership (2)
IFRA Fragrance Transparency List
EPA Safer Chemical Ingredients List (SCIL)
Expert Verdict
Expert safety assessment and concern-level summary for Soyamidopropylamine Oxide.
Regulatory Flags
potential-allergen
epa_safer_alternative
ifra_fragrance
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Soyamidopropylamine Oxide by CAS number or substance name.
Studies
1
Lowest NOAEL
40 mg/kg bw/day
Highest NOAEL
40 mg/kg bw/day
ToxValDB_ECHA_IUCLID
Known Synonyms
Alkyldimethylamine oxides, C12-18-alkyldimethyl
C12-C18 alkyl dimethyl amine oxide
Amine oxides, C12-18-alkyldimethyl
Aromox DMB-W
C12-18-alkyldimethyl amine N-oxides
Synprolam S 3406
Amines, alkyle en C12-18 dimethyles, N-oxydes
Amines, C12-18(even numbered)-alkyldimethyl, N-oxides
Amine, C12-18-Alkyldimethyl-, N-Oxide
aminas, C12-18-alquildimetil, N-oxidos
EINECS 273-281-2
SDA 16-041-00
Chemical Function
Fragrance
Surfactant (surface active agent)
Emulsifier
Regulatory Lists
Europe; Specialty occupational products
IFRA Transparency
SCIL (9/2019)
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Soyamidopropylamine Oxide allowed in the EU?
Soyamidopropylamine Oxide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Soyamidopropylamine Oxide do in cosmetics?
Soyamidopropylamine Oxide functions as: Surfactant (cleansing/foam boosting), antistatic, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 68955-55-5.
What is the NOAEL for Soyamidopropylamine Oxide?
The NOAEL (No Observed Adverse Effect Level) for Soyamidopropylamine Oxide is =40 mg/kg bw/day based on a subchronic study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Soyamidopropylamine Oxide used outside cosmetics?
Soyamidopropylamine Oxide also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Soyamidopropylamine Oxide have different safety status in cosmetics vs industrial chemicals?
Soyamidopropylamine Oxide is classified GHS Danger (H302, H315, H318, H400, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Soyamidopropylamine Oxide compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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