NOAEL Studies Cosmetic Ingredient

Sorbitan Trioleate NOAEL Studies

INCI: SORBITAN TRIOLEATE

CAS: 26266-58-0

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 >39800 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_4743; row=10473; data_type=In Vivo; mixture=Chemical; chemical_name=Sorbitan, tri-(9Z)-9-octadecenoate; preferred_name=Sorbitan trioleate; dtxsid=DTXSID6027892; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6027892; source_file=acute_oral.xlsx
ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =50 mg/kg bw/day Rat injection subchronic; 35 days subchronic QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c62006e4b096bca877fb44; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15041/7/6/5?documentUUID=63bd739b-7323-47bc-99a3-0f23043abca8; YEAR=2012; ORIGINAL_YEAR=2012; STUDY_GROUP=ECHA IUCLID:15851382:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_779c361adf1dec9ec3496b10493f81a2
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier QE6F49RPJ1 UNII - - - chemical {"approval_status":null,"molecular_formula":"C60H108O8","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"QE6F49RPJ1"}
openFDA substances FDA UNII substance identifier QE6F49RPJ1 UNII - - - chemical {"approval_status":null,"molecular_formula":"C60H108O8","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"QE6F49RPJ1"}
openFDA substances FDA UNII substance identifier QE6F49RPJ1 UNII - - - chemical {"approval_status":null,"molecular_formula":"C60H108O8","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"QE6F49RPJ1"}
openFDA substances FDA UNII substance identifier QE6F49RPJ1 UNII - - - chemical {"approval_status":null,"molecular_formula":"C60H108O8","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"QE6F49RPJ1"}