Is Solvent Yellow 44 safe in cosmetics?
Solvent Yellow 44 has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.
Moderate
Cosmetic Ingredient
Solvent Yellow 44
Also known as: 4-Amino-N-(2,4-dimethylphenyl)naphthalene-1,8-dicarboximide, 4-Amino-N-(2',4'-xylyl)-1,8-naphthalimide, EINECS 219-607-9
INCI: SOLVENT YELLOW 44
Solvent Yellow 44 (CAS 2478-20-8) is a cosmetic cosmetic ingredient functioning as Hair colorant (yellow to brown shades); cosmetic colorant. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 2478-20-8 →
Auto-generated CPSR Part A draft with source citations
Function
Hair colorant (yellow to brown shades); cosmetic colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
6-amino-2-(2,4-dimethylphenyl)benzo[de]isoquinoline-1,3-dione
InChIKey
FQLZTPSAVDHUKS-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Not separately listed as a certified color additive by FDA. Note: D\&C Yellow No. 11 (CI 47000, CAS 8003-22-3) is a different Solvent Yellow — do not confuse. Solvent Yellow 44 has no explicit FDA color additive listing
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Solvent Yellow 44.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1277
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1277
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Solvent Yellow 44.
Regulatory Flags
colorant
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
4-Amino-N-(2,4-dimethylphenyl)naphthalene-1,8-dicarboximide
4-Amino-N-(2',4'-xylyl)-1,8-naphthalimide
EINECS 219-607-9
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Solvent Yellow 44 allowed in the EU?
Solvent Yellow 44 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Solvent Yellow 44 do in cosmetics?
Solvent Yellow 44 functions as: Hair colorant (yellow to brown shades); cosmetic colorant. It is classified as a cosmetic ingredient in our database. CAS number: 2478-20-8.
Is Solvent Yellow 44 used outside cosmetics?
Solvent Yellow 44 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Solvent Yellow 44 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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