NOAEL Studies Cosmetic Ingredient

Sodium Propylparaben NOAEL Studies

INCI: SODIUM PROPYLPARABEN

CAS: 35285-69-9

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =980.9 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaaeee4b0a7c65d1b81d2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17005/7/9/2?documentUUID=0c43bffb-b704-49c7-8a02-23979f50e532; YEAR=2018; ORIGINAL_YEAR=2018; STUDY_GROUP=ECHA IUCLID:15855421:M:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0201f05ab70c0ee60f9c370ad31cd134
ToxValDB_ECHA_IUCLID NOAEL =1076.4 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaaeee4b0a7c65d1b81d2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17005/7/9/2?documentUUID=0c43bffb-b704-49c7-8a02-23979f50e532; YEAR=2018; ORIGINAL_YEAR=2018; STUDY_GROUP=ECHA IUCLID:15856239:F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_e1f2eb85220973234b338e968cd355f1
ToxValDB_ECHA_IUCLID NOAEL =1124.6 mg/kg bw/day Rat oral - reproduction developmental QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaaeee4b0a7c65d1b81d2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/17005/7/9/2?documentUUID=0c43bffb-b704-49c7-8a02-23979f50e532; YEAR=2018; ORIGINAL_YEAR=2018; STUDY_GROUP=ECHA IUCLID:15859402:M/F:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6c4d6eaa4ec165e603963a5c37846cf6
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =88.2 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634872:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6285bf163f114fb4e6b48e7d6d2ab9b4
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 625NNB0G9N UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H11O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"625NNB0G9N"}
openFDA substances FDA UNII substance identifier 625NNB0G9N UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H11O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"625NNB0G9N"}
openFDA substances FDA UNII substance identifier 625NNB0G9N UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H11O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"625NNB0G9N"}
openFDA substances FDA UNII substance identifier 625NNB0G9N UNII - - - chemical {"approval_status":null,"molecular_formula":"C10H11O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"625NNB0G9N"}