NOAEL Studies
Cosmetic Ingredient
Sodium Picramate NOAEL Studies
INCI: SODIUM PICRAMATE
CAS: 831-52-7
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
ECHA 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ECHA | NOAEL | =20 | mg/kg bw/day | Rat | oral | short-term; 14 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cc34e4b0a7c65d22960b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/29460/7/6/2?documentUUID=fbe67af3-e65d-44bf-ad48-ea2b46181fb1; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID:15838009:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_ca80b1f9ef6c7370c6f5acfd75c76b8f |
| ECHA | NOAEL | =50 | mg/kg bw/day | Rabbit | dermal | subchronic; 13 weeks | subchronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61e9fe4b096bca877a670; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/29460/7/6/4?documentUUID=fbe67af3-e65d-44bf-ad48-ea2b46181fb1; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID:15826571:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_63463f84a15dece169b79126d9a2d5e5 |
| ECHA | NOAEL | =100 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c96ee4b0a7c65d21cf2b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/29460/7/9/2?documentUUID=fbe67af3-e65d-44bf-ad48-ea2b46181fb1; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID:15856959:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7992ea6fb8c881131d891b5eb2fb8fd3 |
| ECHA | NOEL | =100 | mg/kg bw/day | Rat | dermal | - | developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7d24be4b0a7c65d2327b5; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/29460/7/9/3?documentUUID=fbe67af3-e65d-44bf-ad48-ea2b46181fb1; YEAR=2007; ORIGINAL_YEAR=2007; STUDY_GROUP=ECHA IUCLID:15821831:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_9dd3cd9d4cec4a7a5ee7f2e9a7ea946c |
ToxValDB GESTIS DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB GESTIS DNEL | DNEL systemic | =0.493 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634733:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_bf3b7ab2dced8c4c2c1698488002147d |
openFDA substances 4 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 4988SZV57R | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C6H4N3O5.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4988SZV57R"} |
| openFDA substances | FDA UNII substance identifier | 4988SZV57R | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C6H4N3O5.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4988SZV57R"} |
| openFDA substances | FDA UNII substance identifier | 4988SZV57R | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C6H4N3O5.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4988SZV57R"} |
| openFDA substances | FDA UNII substance identifier | 4988SZV57R | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C6H4N3O5.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"4988SZV57R"} |