Is SODIUM PALMITOYL PROLINE safe in cosmetics?
SODIUM PALMITOYL PROLINE has a safety rating of "GOOD" in our database. EU status: permitted. US status: restricted.
Good
Cosmetic Ingredient
SODIUM PALMITOYL PROLINE
SODIUM PALMITOYL PROLINE (CAS 58725-33-0) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 58725-33-0 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
SODIUM PALMITOYL PROLINE is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin Conditioning
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
sodium (2S)-1-hexadecanoylpyrrolidine-2-carboxylate
InChIKey
GJIFNLAZXVYJDI-FYZYNONXSA-M
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
CIR: SQ - IJT 36(Suppl. 1):17-56, 2017
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Additional Ingredient Properties
1 property record from structured ingredient metadata.
surfactant
{"cas_number": "200442-98-8", "surfactant_type": "anionic", "chemical_class": "sarcosinate", "charge_at_use_ph": "negative", "cmc_critical_micelle_concentration_mm": "5.931112820978763", "hlb_value": "26.0", "foam_volume_ml_ross_miles": "126", "foam_quality": "creamy", "foam_stability_5min_pct": "80", "cleansing_power_rating_1_to_10": "9.247077515248606", "oil_emulsification_capacity": "very good"…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for SODIUM PALMITOYL PROLINE.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
needs-enrichment
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is SODIUM PALMITOYL PROLINE allowed in the EU?
SODIUM PALMITOYL PROLINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does SODIUM PALMITOYL PROLINE do in cosmetics?
SODIUM PALMITOYL PROLINE functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 58725-33-0.
Is SODIUM PALMITOYL PROLINE used outside cosmetics?
SODIUM PALMITOYL PROLINE also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does SODIUM PALMITOYL PROLINE have different safety status in cosmetics vs industrial chemicals?
SODIUM PALMITOYL PROLINE is classified GHS Danger (H315, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
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Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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PALMITOYL ARGININE
Good
Chemical family
Hair Conditioning, Skin Conditioning
SODIUM (ASTROCARYUM VULGARE/EUTERPE OLERACEAE/PALM) FRUIT/(ASTROCARYUM VULGARE/PALM) KERNEL/(ASTROCARYUM MURUMURU/BABASSU/BERTHOLLETIA EXCELSA/CARAPA GUIANENSIS/COCOA/FEVILLEA TRILOBATA/PASSIFLORA EDULIS/THEOBROMA GRANDIFLORUM) SEEDATE
Good
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