Moderate Cosmetic Ingredient GHS Classified

Sodium Oxide

Also known as: Sodium oxide (Na2O), EINECS 215-208-9, UNII-3075U8R23D

INCI: SODIUM OXIDE

Sodium Oxide (CAS 1313-59-3) is a cosmetic cosmetic ingredient functioning as Buffering (pH adjuster). EU Regulation 1223/2009 status: restricted; GHS signal word DANGER. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 1313-59-3 →

Auto-generated CPSR Part A draft with source citations
Function
Buffering (pH adjuster)
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
Na2O
MW
61.979 g/mol
EC Number
215-208-9
PubChem CID
73971
IUPAC Name
disodium;oxygen(2-)
InChIKey
KKCBUQHMOMHUOY-UHFFFAOYSA-N

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Permitted for cosmetic use; no specific restrictions

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Sodium Oxide.

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
DANGER
Pictograms
Corr
Hazard Statements
Causes severe skin burns and eye damage
Short-term Exposure Effects
The substance is corrosive to the eyes, skin and respiratory tract. Corrosive on ingestion. Inhalation of the aerosol may cause lung oedema. See Notes. Medical observation is indicated.
Routes of Exposure
Serious by all routes of exposure.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
ICSC Safety Card
1653
Source: ILO-WHO International Chemical Safety Cards (ICSCs)

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Adsorbent Binder Flux agent pH regulating agent

Expert Verdict

Expert safety assessment and concern-level summary for Sodium Oxide.

Known Synonyms

Sodium oxide (Na2O) EINECS 215-208-9 UNII-3075U8R23D

Chemical Function

pH regulating agent Binder

Regulatory Lists

drinking_water; Europe; manufacturing; plastic_additive

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Sodium Oxide safe in cosmetics?

Sodium Oxide has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.

Is Sodium Oxide allowed in the EU?

Sodium Oxide EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sodium Oxide do in cosmetics?

Sodium Oxide functions as: Buffering (pH adjuster). It is classified as a cosmetic ingredient in our database. CAS number: 1313-59-3.

Is Sodium Oxide classified as hazardous under GHS?

Sodium Oxide carries a GHS signal word of "DANGER". Hazard statements: Causes severe skin burns and eye damage. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.

Is Sodium Oxide used outside cosmetics?

Sodium Oxide also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Sodium Oxide have different safety status in cosmetics vs industrial chemicals?

Sodium Oxide is classified GHS Danger (H314, H318) in the chemicals database but is restricted in EU cosmetics.

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