NOAEL Studies Humectant

Sodium Lactate NOAEL Studies

INCI: SODIUM LACTATE

CAS: 72-17-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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NTP_ICE_acute_oral 3 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
NTP_ICE_acute_oral LD50 =3543 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_9698; row=11026; data_type=In Vivo; mixture=Chemical; chemical_name=Sodium dl-lactate; preferred_name=Sodium DL-lactate; dtxsid=DTXSID6052829; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6052829; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 >5000 mg/kg bw Rat oral acute Rat Acute Oral Toxicity record_id=acute_oral_9702; row=11027; data_type=In Vivo; mixture=Chemical; chemical_name=Sodium dl-lactate; preferred_name=Sodium DL-lactate; dtxsid=DTXSID6052829; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6052829; source_file=acute_oral.xlsx
NTP_ICE_acute_oral LD50 =4936 mg/kg bw Rat oral acute Rat Acute Oral Toxicity OECD eChemPortal (undated); record_id=acute_oral_9700; row=11028; data_type=In Vivo; mixture=Chemical; chemical_name=Sodium dl-lactate; preferred_name=Sodium DL-lactate; dtxsid=DTXSID6052829; url=https://www.echemportal.org/echemportal/; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID6052829; source_file=acute_oral.xlsx
ToxValDB_HESS 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_HESS NOEL =100 mg/kg bw/day Rat oral subchronic; 42 days subchronic STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/60da0dc5e4b0a676289dd33c; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.nite.go.jp/en/chem/qsar/hess_update-e.html; YEAR=2011; ORIGINAL_YEAR=2011; TOXICOLOGICAL_EFFECT=Thyroid Hormone: T4 increase, TSH increase|Histopathology: Stomach-Hyperplasia, squamous, limiting ridge; TOXICOLOGICAL_EFFECT_CATEGORY=clinical chemistry|nonneoplastic histopathology; STUDY_GROUP=HESS:15638691:M:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was manually checked; QC_STATUS=pass; SOURCE_HASH=ToxValhc_d75366853773cbab884495b07362b6f8
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier TU7HW0W0QT UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H5O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TU7HW0W0QT"}
openFDA substances FDA UNII substance identifier TU7HW0W0QT UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H5O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TU7HW0W0QT"}
openFDA substances FDA UNII substance identifier TU7HW0W0QT UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H5O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TU7HW0W0QT"}
openFDA substances FDA UNII substance identifier TU7HW0W0QT UNII - - - chemical {"approval_status":null,"molecular_formula":"C3H5O3.Na","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"TU7HW0W0QT"}