NOAEL Studies
Cosmetic Ingredient
Sodium C10-13 Alkyl Benzenesulfonate NOAEL Studies
INCI: SODIUM C10-13 ALKYL BENZENESULFONATE
CAS: 68411-30-3
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
COSMOS_DB 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| COSMOS_DB | NOAEL | 2 | mg/kg bw/day | mouse | oral | 6-15 Gestation day | Developmental | PAFA; TOXICOLOGY 3:91-106, |
ToxValDB_ECHA_IUCLID 6 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | NOAEL | =300 | mg/kg bw/day | Rat | oral | - | developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac00e4b0a7c65d1bcdc2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14411/7/9/3?documentUUID=7d2b74ff-0044-4bed-8bd6-bb99dd8eb7cf; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15820576_15821200_15821316:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_510a93e8b4fa6e03d70a4002857dd5ad |
| ToxValDB_ECHA_IUCLID | NOAEL | =2 | mg/kg bw/day | Rabbit | oral | - | developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac7be4b0a7c65d1bf5f5; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15438/7/9/3?documentUUID=f340f6ef-ec31-4330-86f2-9821574e5b16; YEAR=2015; ORIGINAL_YEAR=2015; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15820816_15821657_15821813:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_79b379fb0540e58f64ac5c6e7133ebd2 |
| ToxValDB_ECHA_IUCLID | NOAEL | =125 | mg/kg bw/day | Rat | oral | short-term; 30 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7cac7e4b0a7c65d2237b2; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14411/7/6/2?documentUUID=7d2b74ff-0044-4bed-8bd6-bb99dd8eb7cf; YEAR=2002; ORIGINAL_YEAR=2002; TOXICOLOGICAL_EFFECT=body weight and weight gain|clinical biochemistry|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|clinical chemistry|organ weight; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Oral_15832490_15837107_15842263:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_f412a4fa551ceedbc92ca814cd9b0faa |
| ToxValDB_ECHA_IUCLID | NOAEL | =133 | mg/kg bw/day | Mouse | oral | chronic; 9 months | chronic | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaeb0e4b0a7c65d1ca763; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/15879/7/6/2?documentUUID=0c72b004-788c-43e6-a664-fe99f9f4b43b; YEAR=1996; ORIGINAL_YEAR=1996; TOXICOLOGICAL_EFFECT=body weight and weight gain|organ weights and organ / body weight ratios; TOXICOLOGICAL_EFFECT_CATEGORY=body weight|organ weight; STUDY_GROUP=ECHA IUCLID:15845572:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_3f99eba36df1019463c3bb4e4c4a7bf1 |
| ToxValDB_ECHA_IUCLID | NOAEL | =150 | mg/kg bw/day | Monkey | oral | short-term; 28 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c62039e4b096bca8780747; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14411/7/6/5?documentUUID=7d2b74ff-0044-4bed-8bd6-bb99dd8eb7cf; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Other_15852044_15852045_15853086_15853087_15854314_15854315:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_fad722f4d9b7c52dd8efbc63faf8399e |
| ToxValDB_ECHA_IUCLID | NOAEL | =0.5 | mg/kg bw/day | Monkey | oral | short-term; 28 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c62039e4b096bca8780747; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/14411/7/6/5?documentUUID=7d2b74ff-0044-4bed-8bd6-bb99dd8eb7cf; YEAR=2002; ORIGINAL_YEAR=2002; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Other_15852044_15852045_15853086_15853087_15854314_15854315:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_c2f0ebf9b5cd9af6e99d72d3bde9ce49 |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =7.6 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15629997:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_5b5dbd73d13153f1a2df1c4013a8480d |