NOAEL Studies Cosmetic Ingredient

Sclareolide NOAEL Studies

INCI: SCLAREOLIDE

CAS: 564-20-5

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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ToxValDB_ECHA_IUCLID 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_ECHA_IUCLID NOAEL =1000 mg/kg bw/day Rat oral short-term; 28 days short-term QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eae72e4b0a7c65d1c943b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/registration-dossier/-/registered-dossier/23448/7/6/2?documentUUID=747fa67f-df1b-42a8-af28-c415328bddd2; YEAR=1965; ORIGINAL_YEAR=1965; TOXICOLOGICAL_EFFECT=clinical biochemistry|haematology|histopathology: non-neoplastic; TOXICOLOGICAL_EFFECT_CATEGORY=clinical chemistry|hematology|nonneoplastic histopathology; STUDY_GROUP=ECHA IUCLID:15837190:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_16d5dc67dec2a95beee30ecf89431a0f
ToxValDB_GESTIS_DNEL 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
ToxValDB_GESTIS_DNEL DNEL systemic =16.4 mg/m3 Human inhalation - Toxicity Value STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15634606:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_44fcfe82a7abaeb1dca794a259ba6eb0
openFDA substances 4 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 37W4O0O6E6 UNII - - - chemical {"approval_status":null,"molecular_formula":"C16H26O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"37W4O0O6E6"}
openFDA substances FDA UNII substance identifier 37W4O0O6E6 UNII - - - chemical {"approval_status":null,"molecular_formula":"C16H26O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"37W4O0O6E6"}
openFDA substances FDA UNII substance identifier 37W4O0O6E6 UNII - - - chemical {"approval_status":null,"molecular_formula":"C16H26O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"37W4O0O6E6"}
openFDA substances FDA UNII substance identifier 37W4O0O6E6 UNII - - - chemical {"approval_status":null,"molecular_formula":"C16H26O2","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"37W4O0O6E6"}