Salvia Officinalis Leaf Extract

INCI: SALVIA OFFICINALIS LEAF EXTRACT

Salvia Officinalis Leaf Extract (CAS 84082-79-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning, anti-seborrheic, cleansing, oral care, tonic, antioxidant,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 84082-79-1 →

Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, anti-seborrheic, cleansing, oral care, tonic, antioxidant, antimicrobial
Safety Rating
GOOD

Chemistry & Identifiers

EC Number
282-025-9

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes GRAS as essential oil, oleoresin, and natural extractive under 21 CFR 182.20 and 182.10. Sage oil ruled inadequate for OTC astringent GRASE (21 CFR 310.545). No cosmetic restrictions. CIR concluded safe when formulated to be non-sensitizing (Final Report 2022). Max reported use in US VCRP: 0.38% in skin care (213 formulations).

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Salvia Officinalis Leaf Extract.

Calculate MoS for your specific formulation with the MoS Calculator.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Skin Care 0.01–0.38 0.38 CIR (PCPC survey 2020)

Additional Ingredient Properties

1 property record from structured ingredient metadata.

anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-inflammatory", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "Phy…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Antioxidant
Regulatory List Membership (2)
EU Regulated in Personal Care EU Regulated in Personal Care

Expert Verdict

Expert safety assessment and concern-level summary for Salvia Officinalis Leaf Extract.

Regulatory Flags

thujone-content no-mos-calculable no-dermal-absorption-data estrogenic-potential terpene-sensitizer-risk aggregate-exposure-tracking-required

Chemical Function

Antioxidant Deodorizer Softener and conditioner Fragrance Abrasive Biocide

Regulatory Lists

Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care Europe Personal care

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Salvia Officinalis Leaf Extract safe in cosmetics?

Salvia Officinalis Leaf Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Salvia Officinalis Leaf Extract allowed in the EU?

Salvia Officinalis Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Salvia Officinalis Leaf Extract do in cosmetics?

Salvia Officinalis Leaf Extract functions as: Skin conditioning, anti-seborrheic, cleansing, oral care, tonic, antioxidant, antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 84082-79-1.

Is Salvia Officinalis Leaf Extract used outside cosmetics?

Salvia Officinalis Leaf Extract also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Salvia Officinalis Leaf Extract have different safety status in cosmetics vs industrial chemicals?

Salvia Officinalis Leaf Extract is classified GHS Danger (H226, H302, H304, H315, H317, H332, H371, H373) in the chemicals database but is allowed in EU cosmetics.

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(AGARICUS BLAZEI FERMENT + GANODERMA LUCIDUM FERMENT + GANODERMA MULTIPILEUM FERMENT) EXTRACT
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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA) ROOT/CNIDIUM OFFICINALE RHIZOME EXTRACT
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(ANGELICA ACUTILOBA/PAEONIA LACTIFLORA/REHMANNIA GLUTINOSA/SCUTELLARIA BAICALENSIS) ROOT/(CNIDIUM OFFICINALE/COPTIS CHINENSIS) RHIZOME/GARDENIA JASMINOIDES FRUIT/PHELLODENDRON CHINENSE BARK EXTRACT
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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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(APPLE/CITRUS JUNOS/LENTIL/PEAR/PUMPKIN/STRAWBERRY/TOMATO FRUIT)/CORN KERNEL/(ARCTIUM LAPPA/BRASSICA OLERACEA ACEPHALA/CABBAGE/CAMELLIA SINENSIS/MORINGA OLEIFERA/RADISH/SPINACH LEAF)/(SORGHUM BICOLOR LEAF/STEM)/OAT MEAL/POTATO PULP/(CARROT/NELUMBO NUCIFERA/RADISH/WILD YAM ROOT)/(AMARANTHUS HYPOCHONDRIACUS/CASHEW/CICER ARIETINUM/COIX LACRYMA-JOBI MA-YUEN /MACADAMIA TERNIFOLIA/PHASEOLUS ANGULARIS/PISTACIA VERA/RHYNCHOSIA NULUBILIS/RICE/SESAME/SETARIA ITALICA/SOYBEAN/SWEET ALMOND/WHEAT SEED)/HORDEUM VULGARE SPROUT/CYPERUS ESCULENTUS TUBER/ARTEMISIA PRINCEPS/BROCCOLI/CHENOPODIUM QUINOA/ENTEROMORPHA COMPRESSA/HORDEUM VULGARE/IPOMOEA BATATAS/LAMINARIA JAPONICA/LENTINUS EDODES/PLEUROTUS OSTREATUS/PORPHYRA TENERA/UNDARIA PINNATIFIDA EXTRACT
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Tonic, skin conditioning, fragrance

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