Is Rosmanol safe in cosmetics?
Rosmanol has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Rosmanol
INCI: ROSMARINUS OFFICINALIS LEAF EXTRACT
Rosmanol (CAS 80225-53-2) is a cosmetic cosmetic ingredient functioning as Antioxidant, Anti-Wrinkle, Anti-Elastase, Anti-Tyrosinase. EU Regulation 1223/2009 status: permitted, max 0.07-0.13% in rosemary CO2 extracts; no limits for rosemary extracts. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 80225-53-2 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Anti-Wrinkle, Anti-Elastase, Anti-Tyrosinase
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(1R,8S,9S,10S)-3,4,8-trihydroxy-11,11-dimethyl-5-propan-2-yl-16-oxatetracyclo[7.5.2.01,10.02,7]hexadeca-2,4,6-trien-15-one
InChIKey
LCAZOMIGFDQMNC-FORWCCJISA-N
Regulatory Status
EU EU Status
permitted
EU Max Conc.
0.07-0.13% in rosemary CO2 extracts; no limits for rosemary extracts
US US Status
permitted
US Notes
Rosmarinus officinalis GRAS (21 CFR 182.10). CIR: rosemary-derived safe when formulated to be nonsensitizing (2018).
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Rosmanol.
Calculate MoS for your specific formulation with the MoS Calculator.
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Face Cream | 0.01–0.5 | 1 | CIR/VCRP |
Additional Ingredient Properties
1 property record from structured ingredient metadata.
anti_aging
{"anti_aging_claim": "antioxidant-protection, anti-wrinkle", "mechanism_of_action": "Carnosic acid, rosmarinic acid", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "Mild", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytotherapy Research,…
Expert Verdict
Expert safety assessment and concern-level summary for Rosmanol.
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ROSMANOL
ChEMBL ID
CHEMBL507166
Frequently Asked Questions
Is Rosmanol allowed in the EU?
Rosmanol EU regulatory status: permitted. Maximum allowed concentration: 0.07-0.13% in rosemary CO2 extracts; no limits for rosemary extracts. This is based on EU Regulation 1223/2009 and its amendments.
What does Rosmanol do in cosmetics?
Rosmanol functions as: Antioxidant, Anti-Wrinkle, Anti-Elastase, Anti-Tyrosinase. It is classified as a cosmetic ingredient in our database. CAS number: 80225-53-2.
Is Rosmanol used outside cosmetics?
Rosmanol also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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