Is Riboflavin Butyrate safe in cosmetics?
Riboflavin Butyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Riboflavin Butyrate
Also known as: EINECS 212-034-5, Riboflavine tetrabutyrate, UNII-F211C9MSGY
INCI: RIBOFLAVIN BUTYRATE
Riboflavin Butyrate (CAS 752-56-7) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 752-56-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(2R,3S,4S)-2,3,4-tri(butanoyloxy)-5-(7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10-yl)pentyl] butanoate
InChIKey
MJNIWUJSIGSWKK-BBANNHEPSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA under 21 CFR. No CIR review specific to this ester. Riboflavin is GRAS for food use.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Riboflavin Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Riboflavin Butyrate.
Known Synonyms
EINECS 212-034-5
Riboflavine tetrabutyrate
UNII-F211C9MSGY
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1325863
Frequently Asked Questions
Is Riboflavin Butyrate allowed in the EU?
Riboflavin Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Riboflavin Butyrate do in cosmetics?
Riboflavin Butyrate functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 752-56-7.
Is Riboflavin Butyrate used outside cosmetics?
Riboflavin Butyrate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Riboflavin Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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Skin conditioning [^1_17]
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RIBES NIGRUM BUD WAX
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Browse nearby
Not Reported
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