Is Rhodiola Rosea Root Extract safe in cosmetics?
Rhodiola Rosea Root Extract has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Rhodiola Rosea Root Extract
INCI: RHODIOLA ROSEA ROOT EXTRACT
Rhodiola Rosea Root Extract (CAS None) is a cosmetic cosmetic ingredient functioning as Skin adaptogen, anti-aging active, antioxidant. Key bioactives: salidroside,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS None →
Auto-generated CPSR Part A draft with source citations
Function
Skin adaptogen, anti-aging active, antioxidant. Key bioactives: salidroside, rosavins. Mechanisms: stress-skin axis regulation, antioxidant defense, anti-senescence.
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No FDA restrictions. Formal topical adaptogen classification per 2025 PRISMA systematic review. HPLC salidroside and rosavin quantification required per WHO 2025 guidelines.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Rhodiola Rosea Root Extract.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
3 property records from structured ingredient metadata.
acne
{"cas_number": "97404-52-9", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction…
anti_pollution
{"cas_number": "97404-52-9", "ingredient_class": "Nrf2_activator", "primary_mechanism": "enzyme_induction", "pollution_types_targeted": "PM2_5/oxidative_stress", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation":…
self_tanning
{"cas_number": "97404-52-9", "ingredient_class": "tan_extender", "tanning_mechanism": "other", "color_development_onset_hours": "0.0", "full_color_development_hours": "0", "color_duration_days": "0", "DHA_concentration_if_applicable_pct": "0", "erythrulose_concentration_pct": "0", "pH_dependent_color": "no", "formaldehyde_release_concern": "no", "formaldehyde_release_ppm": "0", "AGE_formation_conc…
Expert Verdict
Expert safety assessment and concern-level summary for Rhodiola Rosea Root Extract.
Regulatory Flags
adaptogen
salidroside-content
rosavin-content
stress-skin-axis
anti-senescence
antioxidant
hplc-quantification-required
who-2025-compliance
in-vitro-evidence
Frequently Asked Questions
Is Rhodiola Rosea Root Extract allowed in the EU?
Rhodiola Rosea Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Rhodiola Rosea Root Extract do in cosmetics?
Rhodiola Rosea Root Extract functions as: Skin adaptogen, anti-aging active, antioxidant. Key bioactives: salidroside, rosavins. Mechanisms: stress-skin axis regulation, antioxidant defense, anti-senescence.. It is classified as a cosmetic ingredient in our database. CAS number: None.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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