Is rh-Polypeptide-11 safe in cosmetics?
rh-Polypeptide-11 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
rh-Polypeptide-11
INCI: RH-POLYPEPTIDE-11 (NOW RECLASSIFIED AS SH-POLYPEPTIDE-11; FORMER RH-OLIGOPEPTIDE-13)
rh-Polypeptide-11 (CAS 62031-54-3) is a cosmetic cosmetic ingredient functioning as Skin conditioning, skin protecting; recombinant analog of acidic Fibroblast. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 62031-54-3 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, skin protecting; recombinant analog of acidic Fibroblast Growth Factor (aFGF) — stimulates fibroblast proliferation, collagen/elastin production, hair growth
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2R)-N-[(2R)-1-[[(2R)-6-amino-1-[[(2R)-6-amino-1-[(2R)-2-(hydroxymethyl)pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]-2-[[2-[[(2R)-2-[[(2R)-1-[(2R)-2-[[(2R)-4-amino-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-4-oxobutanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]acetyl]amino]butanediamide
InChIKey
MSJSNXQCIRMHFJ-WIRNGOBFSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restriction; permitted under general cosmetic rules
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for rh-Polypeptide-11.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for rh-Polypeptide-11.
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is rh-Polypeptide-11 allowed in the EU?
rh-Polypeptide-11 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does rh-Polypeptide-11 do in cosmetics?
rh-Polypeptide-11 functions as: Skin conditioning, skin protecting; recombinant analog of acidic Fibroblast Growth Factor (aFGF) — stimulates fibroblast proliferation, collagen/elastin production, hair growth. It is classified as a cosmetic ingredient in our database. CAS number: 62031-54-3.
Compliance Tools
Check rh-Polypeptide-11 compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Excellent
Chemical family
Skin Conditioning, Hair Conditioning
RH-POLYPEPTIDE-11 DIPEPTIDE-19 OLIGOPEPTIDE-91 HEXAPEPTIDE-40
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