Is Retinoxytrimethylsilane safe in cosmetics?
Retinoxytrimethylsilane has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Retinoxytrimethylsilane
Also known as: Retin, 15-[(trimethylsilyl)oxy]-, (11-cis,13-cis)-, Retinol, trans-7,trans-9,cis-11,cis-13-, Retinol, trans-7,trans-9,cis-11,cis-13- (8ci)
INCI: RETINOXYTRIMETHYLSILANE
Retinoxytrimethylsilane (CAS 16729-19-4) is a cosmetic cosmetic ingredient functioning as Skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 16729-19-4 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
[(2Z,4Z,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoxy]-trimethylsilane
InChIKey
MKFYWDRIINZECV-HHEUHLPGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated; general cosmetic ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Retinoxytrimethylsilane.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Retinoxytrimethylsilane.
Known Synonyms
Retin, 15-[(trimethylsilyl)oxy]-, (11-cis,13-cis)-
Retinol, trans-7,trans-9,cis-11,cis-13-
Retinol, trans-7,trans-9,cis-11,cis-13- (8ci)
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Retinoxytrimethylsilane allowed in the EU?
Retinoxytrimethylsilane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Retinoxytrimethylsilane do in cosmetics?
Retinoxytrimethylsilane functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 16729-19-4.
Is Retinoxytrimethylsilane used outside cosmetics?
Retinoxytrimethylsilane also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Retinoxytrimethylsilane compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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