Is Quillaja Saponaria Bark safe in cosmetics?
Quillaja Saponaria Bark has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted. 3 toxicological study endpoint(s) are available in our database.
Quillaja Saponaria Bark
Also known as: EINECS 273-620-4, Quillaja saponaria pollen
INCI: QUILLAJA SAPONARIA BARK
Quillaja Saponaria Bark (CAS 68990-67-0) is a cosmetic cosmetic ingredient functioning as Emulsifying. NOAEL 1500 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and food safety data.
View industrial chemical safety profile for CAS 68990-67-0 →
Auto-generated CPSR Part A draft with source citations
Function
Emulsifying
Safety Rating
GOOD
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS as food additive (21 CFR); permitted in cosmetics under general provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Quillaja Saponaria Bark.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Quillaja Saponaria Bark. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1175 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 1180 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 2200 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Quillaja Saponaria Bark across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-dandruff
Cleaning agent
Deodorizer
Emulsifier
Flavouring and nutrient
Foamant
Fragrance
Humectant
Softener and conditioner
Surfactant (surface active agent)
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Quillaja Saponaria Bark.
Regulatory Flags
natural-origin
ifra_fragrance
fda_food_additive
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Quillaja Saponaria Bark by CAS number or substance name.
Studies
3
Lowest NOAEL
1175 mg/kg bw/day
Highest NOAEL
2200 mg/kg bw/day
COSMOS_DB
Known Synonyms
EINECS 273-620-4
Quillaja saponaria pollen
Chemical Function
Fragrance
Surfactant (surface active agent)
Deodorizer
Softener and conditioner
Emulsifier
Cleaning agent
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
IFRA Transparency
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Quillaia extract
E Number
E999
ADI
5 mg/kg bw
Food Category
emulsifier
Frequently Asked Questions
Is Quillaja Saponaria Bark allowed in the EU?
Quillaja Saponaria Bark EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Quillaja Saponaria Bark do in cosmetics?
Quillaja Saponaria Bark functions as: Emulsifying. It is classified as a cosmetic ingredient in our database. CAS number: 68990-67-0.
What is the NOAEL for Quillaja Saponaria Bark?
The NOAEL (No Observed Adverse Effect Level) for Quillaja Saponaria Bark is 1175 mg/kg bw/day based on a Carcinogenicity study via oral route in rat. A total of 3 study endpoints are available. Source: COSMOS_DB.
Is Quillaja Saponaria Bark used outside cosmetics?
Quillaja Saponaria Bark also appears in industrial chemical safety and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Quillaja Saponaria Bark compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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