Is Quaternium-22 safe in cosmetics?
Quaternium-22 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Quaternium-22
INCI: QUATERNIUM-22
Quaternium-22 (CAS 51812-80-7 [^1_14]) is a cosmetic cosmetic ingredient functioning as Antistatic, Film Forming, Hair Conditioning [^1_15]. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 51812-80-7 [^1_14] →
Auto-generated CPSR Part A draft with source citations
Function
Antistatic, Film Forming, Hair Conditioning [^1_15]
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; CIR reviewed — safe as used at ≤ ~5% solids, with impurity limits (DMAPA ≤ 0.2%, ECH ≤ 0.0087%) [^1_16]
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Quaternium-22.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Quaternium-22.
Regulatory Flags
potential-allergen
Frequently Asked Questions
Is Quaternium-22 allowed in the EU?
Quaternium-22 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Quaternium-22 do in cosmetics?
Quaternium-22 functions as: Antistatic, Film Forming, Hair Conditioning [^1_15]. It is classified as a cosmetic ingredient in our database. CAS number: 51812-80-7 [^1_14].
Compliance Tools
Check Quaternium-22 compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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