Is Pyroglutamylamidoethyl Indole safe in cosmetics?
Pyroglutamylamidoethyl Indole has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Pyroglutamylamidoethyl Indole
INCI: PYROGLUTAMYLAMIDOETHYL INDOLE
Pyroglutamylamidoethyl Indole (CAS 62062-65-1) is a cosmetic cosmetic ingredient functioning as Skin Conditioning; Hair Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 62062-65-1 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Pyroglutamylamidoethyl Indole is classified GHS Danger (H302, H315, H319, H335, H371, H226, H318) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Skin Conditioning; Hair Conditioning
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
propan-2-yl (2S)-2-aminopropanoate;hydrochloride
InChIKey
YAQKNCSWDMGPOY-JEDNCBNOSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated; permitted as cosmetic ingredient
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Pyroglutamylamidoethyl Indole.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Intermediate
Tonnage Band
Intermediate use only
Substance Type
SUBSTANCE
SVHC Candidate
No
Expert Verdict
Expert safety assessment and concern-level summary for Pyroglutamylamidoethyl Indole.
Frequently Asked Questions
Is Pyroglutamylamidoethyl Indole allowed in the EU?
Pyroglutamylamidoethyl Indole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pyroglutamylamidoethyl Indole do in cosmetics?
Pyroglutamylamidoethyl Indole functions as: Skin Conditioning; Hair Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 62062-65-1.
Is Pyroglutamylamidoethyl Indole used outside cosmetics?
Pyroglutamylamidoethyl Indole also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Pyroglutamylamidoethyl Indole have different safety status in cosmetics vs industrial chemicals?
Pyroglutamylamidoethyl Indole is classified GHS Danger (H302, H315, H319, H335, H371, H226, H318) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Pyroglutamylamidoethyl Indole compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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