Is Pyridyloxide T-Butylnitrone safe in cosmetics?
Pyridyloxide T-Butylnitrone has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Pyridyloxide T-Butylnitrone
INCI: PYRIDYLOXIDE T-BUTYLNITRONE [^1_17]
Pyridyloxide T-Butylnitrone (CAS 66893-81-0 [^1_17]) is a cosmetic cosmetic ingredient functioning as Antioxidant (radical spin-trap agent); structurally analogous to PBN (Phenyl. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 66893-81-0 [^1_17] →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant (radical spin-trap agent); structurally analogous to PBN (Phenyl T-Butylnitrone) but with a pyridine N-oxide ring for enhanced radical scavenging [^1_18][^1_17]
Safety Rating
MODERATE
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics; no specific FDA monograph
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Pyridyloxide T-Butylnitrone.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Pyridyloxide T-Butylnitrone.
Frequently Asked Questions
Is Pyridyloxide T-Butylnitrone allowed in the EU?
Pyridyloxide T-Butylnitrone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Pyridyloxide T-Butylnitrone do in cosmetics?
Pyridyloxide T-Butylnitrone functions as: Antioxidant (radical spin-trap agent); structurally analogous to PBN (Phenyl T-Butylnitrone) but with a pyridine N-oxide ring for enhanced radical scavenging [^1_18][^1_17]. It is classified as a cosmetic ingredient in our database. CAS number: 66893-81-0 [^1_17].
Compliance Tools
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Substance Compliance
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