NOAEL Studies
Cosmetic Ingredient
PPG-40 Butyl Ether NOAEL Studies
INCI: PPG-40 BUTYL ETHER
CAS: 9003-13-8
Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.
NTP_ICE_acute_dermal 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_dermal | GHS classification | 5 | unitless | Rat | Dermal | - | In Vivo; Rat Acute Dermal Toxicity | sheet=Data; excel_row=986; Record_ID=acute_dermal_260; Data_Type=In Vivo; Formulation_ID=MIX253; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10.0; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Rat Acute Dermal Toxicity; Endpoint=GHS classification; Response=5.0; Response_Unit=Unitless; Species=Rat; Route=Dermal; Reference=FIFRA data; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
| NTP_ICE_acute_dermal | LD50 | >5000 | mg/kg | Rat | Dermal | - | In Vivo; Rat Acute Dermal Toxicity | sheet=Data; excel_row=987; Record_ID=acute_dermal_260; Data_Type=In Vivo; Formulation_ID=MIX253; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10.0; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Rat Acute Dermal Toxicity; Endpoint=LD50; Response_Modifier=>; Response=5000.0; Response_Unit=mg/kg; Species=Rat; Route=Dermal; Reference=FIFRA data; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
NTP_ICE_acute_inhalation 2 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_inhalation | EPA Classification | 4 | unitless | - | Inhalation | - | In Vivo; AcuteInhal6pack; Rat Acute Inhalation Toxicity | sheet=Data; excel_row=2123; Record_ID=acute_inhalation_202; Data_Type=In Vivo; Internal_Data_Source=AcuteInhal6pack; Formulation_ID=MIX253; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10.0; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Rat Acute Inhalation Toxicity; Endpoint=EPA Classification; Response=4; Response_Unit=Unitless; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
| NTP_ICE_acute_inhalation | LC50 | >2.06 | mg/L | - | Inhalation | - | In Vivo; AcuteInhal6pack; Rat Acute Inhalation Toxicity | sheet=Data; excel_row=2124; Record_ID=acute_inhalation_202; Data_Type=In Vivo; Internal_Data_Source=AcuteInhal6pack; Formulation_ID=MIX253; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10.0; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Rat Acute Inhalation Toxicity; Endpoint=LC50; Response_Modifier=>; Response=2.06; Response_Unit=mg/L; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
NTP_ICE_acute_oral 3 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_acute_oral | EPA classification | =3 | Unitless | Rat (Male) | oral | acute | Rat Acute Oral Toxicity | Studies submitted to EPA in support of pesticide registration applications (undated); record_id=acute_oral_12621; row=6077; data_type=In Vivo; mixture=Mixture; formulation_id=MIX253; formulation_name=Gordon's Horse & Pony Spray; chemical_name=Butoxypolypropylene glycol; preferred_name=Butoxypolypropylene glycol; percent_active_ingredient=10.0; dtxsid=DTXSID3034404; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404; source_file=acute_oral.xlsx |
| NTP_ICE_acute_oral | GHS classification | =5 | Unitless | Rat (Female) | oral | acute | Rat Acute Oral Toxicity | Studies submitted to EPA in support of pesticide registration applications (undated); record_id=acute_oral_12619; row=6078; data_type=In Vivo; mixture=Mixture; formulation_id=MIX253; formulation_name=Gordon's Horse & Pony Spray; chemical_name=Butoxypolypropylene glycol; preferred_name=Butoxypolypropylene glycol; percent_active_ingredient=10.0; dtxsid=DTXSID3034404; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404; source_file=acute_oral.xlsx |
| NTP_ICE_acute_oral | LD50 | >2000 | mg/kg bw | Rat (Female) | oral | acute | Rat Acute Oral Toxicity | Studies submitted to EPA in support of pesticide registration applications (undated); record_id=acute_oral_12619; row=6080; data_type=In Vivo; mixture=Mixture; formulation_id=MIX253; formulation_name=Gordon's Horse & Pony Spray; chemical_name=Butoxypolypropylene glycol; preferred_name=Butoxypolypropylene glycol; percent_active_ingredient=10.0; dtxsid=DTXSID3034404; url_comptox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404; source_file=acute_oral.xlsx |
NTP_ICE_eye_irritation 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_eye_irritation | EPA Classification | 4 | unitless | Rabbit | Ocular | - | In Vivo; Draize Eye Irritation/Corrosion Test | sheet=Data; excel_row=1128; Record_ID=eye_irritation_638; Data_Type=In Vivo; Formulation_ID=EyeIrritation6pack_PID520; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10.0; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Draize Eye Irritation/Corrosion Test; Endpoint=EPA Classification; Response=4; Response_Unit=Unitless; Species=Rabbit; Reference=FIFRA data; URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
NTP_ICE_skin_irritation 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_skin_irritation | EPA classification | 4 | unitless | Rabbit | Dermal | - | In Vivo; Draize Skin Irritation/Corrosion Test | sheet=Data_invivo; excel_row=786; Record_ID=skin_irritation_invivo_302; Data_Type=In Vivo; Formulation_ID=MIX253; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Draize Skin Irritation/Corrosion Test; Endpoint=EPA classification; Response=4; Response_Unit=Unitless; Species=Rabbit; Reference=FIFRA (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
NTP_ICE_skin_sensitization 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| NTP_ICE_skin_sensitization | GHS Classification | 1 | unitless | Guinea pig | Dermal | - | In Vivo; SkinSensitization6pack; Guinea Pig Maximization/Buehler | sheet=Data_invivo; excel_row=1056; Record_ID=skin_sensitization_invivo_208; Data_Type=In Vivo; Internal_Data_Source=SkinSensitization6pack; Formulation_ID=MIX253; Formulation_Name=Gordon's Horse & Pony Spray; Percent_Active_Ingredient=10; Mixture=Mixture; DTXSID=DTXSID3034404; Assay=Guinea Pig Maximization/Buehler; Endpoint=GHS Classification; Response=1; Response_Unit=Unitless; Species=Guinea pig; Route=Dermal; Reference=FIFRA (undated); URL_CompTox=https://comptox.epa.gov/dashboard/chemical/details/DTXSID3034404 |
ToxValDB_ECHA_IUCLID 16 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_ECHA_IUCLID | LEL | =150 | mg/kg bw/day | Rabbit | oral | - | developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac86e4b0a7c65d1bf9af; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; TOXICOLOGICAL_EFFECT=fetus: fetal/pup body weight changes|fetus: changes in litter size and weights; TOXICOLOGICAL_EFFECT_CATEGORY=development; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15821858_15823521:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_90e3660f53b4a2908fbcdefc20efcd30 |
| ToxValDB_ECHA_IUCLID | LEL | ~115 | mg/kg bw/day | Rabbit | oral | - | reproduction developmental | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac86e4b0a7c65d1bf9af; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; TOXICOLOGICAL_EFFECT=maternal: mortality; TOXICOLOGICAL_EFFECT_CATEGORY=mortality/survival; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15823437_15823656:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_5b5d2d3169ccb93c2283f25922e494a8 |
| ToxValDB_ECHA_IUCLID | LOAEL | =250 | mg/kg bw/day | Rat | dermal | short-term; 4 weeks | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61f4ce4b096bca877d165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826817_15826818_15826819:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_02aaa046a677f3d9c53c1ef5409ed977 |
| ToxValDB_ECHA_IUCLID | LOAEL | =50 | mg/kg bw/day | Rat | dermal | short-term; 4 weeks | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61f4ce4b096bca877d165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826817_15826818_15826819:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_523aacc80a2f537d380b9da5541e2b17 |
| ToxValDB_ECHA_IUCLID | NOAEL | =115 | mg/kg bw/day | Rabbit | oral | - | developmental | GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac86e4b0a7c65d1bf9ab; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15821858_15823521:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_7b5c4bc62ff2e245290cb341976dec5e |
| ToxValDB_ECHA_IUCLID | NOAEL | =50 | mg/kg bw/day | Rabbit | oral | - | reproduction developmental | GUIDELINE=OECD Guideline 414 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac86e4b0a7c65d1bf9ab; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Developmental Toxicity Teratogenicity_15823437_15823656:F:-maternal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_b0923999060be7caf744c4da5c09ad5a |
| ToxValDB_ECHA_IUCLID | NOAEL | =350 | mg/kg bw/day | Rat | oral | - | developmental | GUIDELINE=EPA OPPTS 870.3700 (Prenatal Developmental Toxicity Study); QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eac86e4b0a7c65d1bf9a7; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID:15825395:-:-fetal; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_4f7940fbcb58b9c6cf6d7322d44954b5 |
| ToxValDB_ECHA_IUCLID | NOAEL | >=250 | mg/kg bw/day | Rat | dermal | acute; 6 hours | acute | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61e09e4b096bca877812b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826380_15826381:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_d311f2dec9da34624f68f7576d2afa38 |
| ToxValDB_ECHA_IUCLID | NOAEL | =80 | mg/kg bw/day | Rat | dermal | acute; 6 hours | acute | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61e09e4b096bca877812b; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826380_15826381:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_0d4acec90466281313a5b2cab8f00350 |
| ToxValDB_ECHA_IUCLID | NOAEL | =100 | mg/kg bw/day | Rat | dermal | short-term; 4 weeks | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/67c61f4ce4b096bca877d165; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Repeated Dose Toxicity Dermal_15826817_15826818_15826819:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_7089d876d4eeff480676f991cba7895d |
| ToxValDB_ECHA_IUCLID | NOAEL | =150 | mg/kg bw/day | Rat | oral | short-term; 29 days | short-term | QUALITY=2 (reliable with restrictions); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eaf51e4b0a7c65d1cd70e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=f613700f-1a0a-4dc1-bfd8-bc780e5738ef; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID:15850926:M/F:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_61e3a7726e42132d88b38ffd59fd2182 |
| ToxValDB_ECHA_IUCLID | NOAEL | =30 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c95ee4b0a7c65d21cb4f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855570_15856368:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_fea337577fb52d1f22ff426adaf3a3ef |
| ToxValDB_ECHA_IUCLID | NOAEL | =300 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab87e4b0a7c65d1ba987; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; TOXICOLOGICAL_EFFECT=P0: reproductive function (oestrous cycle)|P0: reproductive performance; TOXICOLOGICAL_EFFECT_CATEGORY=reproduction; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855148_15855712_15855812_15856564_15863218:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_6b0b83f8dc44fd8389b804ceac528d05 |
| ToxValDB_ECHA_IUCLID | NOAEL | =10 | mg/kg bw/day | Rat | dermal | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/66a7c95ee4b0a7c65d21cb4f; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15855570_15856368:M/F:P0-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_1adb3d7db50ab4da3d8425ff24632ac9 |
| ToxValDB_ECHA_IUCLID | NOAEL | =450 | mg/kg bw/day | Rat | oral | - | reproduction developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab87e4b0a7c65d1ba983; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID_dup_Toxicity Reproduction_15858421_15858680:-:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_18db2abd4670458b429cd22b1fb8819d |
| ToxValDB_ECHA_IUCLID | NOAEL | =600 | mg/kg bw/day | Rat | oral | - | developmental | QUALITY=1 (reliable without restriction); STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/669eab87e4b0a7c65d1ba987; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://echa.europa.eu/; SUBSOURCE_URL=https://echa.europa.eu/en/registration-dossier/-/registered-dossier/2120?documentUUID=294947b1-3cd2-4518-972f-bf0498139007; YEAR=2011; ORIGINAL_YEAR=2011; STUDY_GROUP=ECHA IUCLID:15862312:-:F1-; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, and this record was expert reviewed; QC_STATUS=pass; SOURCE_HASH=ToxValhc_a3957cea064b9a82a00f01c26fb3cdc2 |
ToxValDB_EPA_OPP 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_EPA_OPP | PAD (RfD) | =1.2 | mg/kg bw/day | Human | oral | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/63d99625e4b02a0c3a37c5d8; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.epa.gov/sdwa/2021-human-health-benchmarks-pesticides; YEAR=2021; ORIGINAL_YEAR=2021; STUDY_GROUP=EPA OPP:15789112:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_2ab926be50532a726b8e81e04de0e08d |
ToxValDB_GESTIS_DNEL 1 endpoint
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| ToxValDB_GESTIS_DNEL | DNEL systemic | =2.9 | mg/m3 | Human | inhalation | - | Toxicity Value | STORED_SOURCE_RECORD=https://clowder.edap-cluster.com/files/6543dd69e4b045b9ff7cd87e; RECORD_SOURCE_LEVEL=Extraction document; SOURCE_URL=https://www.dguv.de/ifa/gestis/gestis-dnel-liste/index-2.jsp; STUDY_GROUP=GESTIS DNEL:15635542:-:--; QC_CATEGORY=Programmatically extracted from structured data source; Source overall passed QC, but this record was not manually checked; QC_STATUS=not determined; SOURCE_HASH=ToxValhc_282d560bba791f792d37bbb2938d9f4f |
openFDA substances 43 endpoints
| Source | Endpoint Type | Value | Unit | Species | Route | Duration | Study Type | Reference |
|---|---|---|---|---|---|---|---|---|
| openFDA substances | FDA UNII substance identifier | 400G2Q040G | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"400G2Q040G"} |
| openFDA substances | FDA UNII substance identifier | K0N34Z34O8 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C13H28O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"K0N34Z34O8"} |
| openFDA substances | FDA UNII substance identifier | R199TJT95T | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"R199TJT95T"} |
| openFDA substances | FDA UNII substance identifier | C0MP061QDX | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"C0MP061QDX"} |
| openFDA substances | FDA UNII substance identifier | V2Z8NAZ8T1 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"V2Z8NAZ8T1"} |
| openFDA substances | FDA UNII substance identifier | 5P40RLJ3YU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5P40RLJ3YU"} |
| openFDA substances | FDA UNII substance identifier | 80JPU34G30 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"80JPU34G30"} |
| openFDA substances | FDA UNII substance identifier | PBU1N1UU7E | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"PBU1N1UU7E"} |
| openFDA substances | FDA UNII substance identifier | 5532T1CST6 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5532T1CST6"} |
| openFDA substances | FDA UNII substance identifier | 18HJT78S09 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"18HJT78S09"} |
| openFDA substances | FDA UNII substance identifier | 6A70KLA0NP | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"6A70KLA0NP"} |
| openFDA substances | FDA UNII substance identifier | 400G2Q040G | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"400G2Q040G"} |
| openFDA substances | FDA UNII substance identifier | 400G2Q040G | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"400G2Q040G"} |
| openFDA substances | FDA UNII substance identifier | K0N34Z34O8 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C13H28O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"K0N34Z34O8"} |
| openFDA substances | FDA UNII substance identifier | K0N34Z34O8 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C13H28O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"K0N34Z34O8"} |
| openFDA substances | FDA UNII substance identifier | R199TJT95T | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"R199TJT95T"} |
| openFDA substances | FDA UNII substance identifier | R199TJT95T | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"R199TJT95T"} |
| openFDA substances | FDA UNII substance identifier | C0MP061QDX | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"C0MP061QDX"} |
| openFDA substances | FDA UNII substance identifier | C0MP061QDX | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"C0MP061QDX"} |
| openFDA substances | FDA UNII substance identifier | V2Z8NAZ8T1 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"V2Z8NAZ8T1"} |
| openFDA substances | FDA UNII substance identifier | V2Z8NAZ8T1 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"V2Z8NAZ8T1"} |
| openFDA substances | FDA UNII substance identifier | 400G2Q040G | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"400G2Q040G"} |
| openFDA substances | FDA UNII substance identifier | 5P40RLJ3YU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5P40RLJ3YU"} |
| openFDA substances | FDA UNII substance identifier | 5P40RLJ3YU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5P40RLJ3YU"} |
| openFDA substances | FDA UNII substance identifier | K0N34Z34O8 | UNII | - | - | - | chemical | {"approval_status":null,"molecular_formula":"C13H28O4","source_table":"substance_identifiers_fda","substance_class":"chemical","unii_code":"K0N34Z34O8"} |
| openFDA substances | FDA UNII substance identifier | 80JPU34G30 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"80JPU34G30"} |
| openFDA substances | FDA UNII substance identifier | R199TJT95T | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"R199TJT95T"} |
| openFDA substances | FDA UNII substance identifier | PBU1N1UU7E | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"PBU1N1UU7E"} |
| openFDA substances | FDA UNII substance identifier | PBU1N1UU7E | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"PBU1N1UU7E"} |
| openFDA substances | FDA UNII substance identifier | C0MP061QDX | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"C0MP061QDX"} |
| openFDA substances | FDA UNII substance identifier | V2Z8NAZ8T1 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"V2Z8NAZ8T1"} |
| openFDA substances | FDA UNII substance identifier | 5P40RLJ3YU | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5P40RLJ3YU"} |
| openFDA substances | FDA UNII substance identifier | 80JPU34G30 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"80JPU34G30"} |
| openFDA substances | FDA UNII substance identifier | 5532T1CST6 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5532T1CST6"} |
| openFDA substances | FDA UNII substance identifier | 5532T1CST6 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5532T1CST6"} |
| openFDA substances | FDA UNII substance identifier | PBU1N1UU7E | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"PBU1N1UU7E"} |
| openFDA substances | FDA UNII substance identifier | 18HJT78S09 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"18HJT78S09"} |
| openFDA substances | FDA UNII substance identifier | 18HJT78S09 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"18HJT78S09"} |
| openFDA substances | FDA UNII substance identifier | 6A70KLA0NP | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"6A70KLA0NP"} |
| openFDA substances | FDA UNII substance identifier | 6A70KLA0NP | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"6A70KLA0NP"} |
| openFDA substances | FDA UNII substance identifier | 5532T1CST6 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"5532T1CST6"} |
| openFDA substances | FDA UNII substance identifier | 18HJT78S09 | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"18HJT78S09"} |
| openFDA substances | FDA UNII substance identifier | 6A70KLA0NP | UNII | - | - | - | polymer | {"approval_status":null,"molecular_formula":null,"source_table":"substance_identifiers_fda","substance_class":"polymer","unii_code":"6A70KLA0NP"} |