Moderate Cosmetic Ingredient NOAEL Data

PPG-3 Glyceryl Ether Triacrylate

INCI: PPG-3 GLYCERYL ETHER TRIACRYLATE

PPG-3 Glyceryl Ether Triacrylate (CAS 52408-84-1) is a cosmetic cosmetic ingredient functioning as Film forming. Reported NOAEL =150 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 52408-84-1 →

Auto-generated CPSR Part A draft with source citations
Function
Film forming
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C21H32O9
MW
428.5 g/mol
EC Number
500-114-5
PubChem CID
93276
IUPAC Name
3-[2,3-bis(3-prop-2-enoyloxypropoxy)propoxy]propyl prop-2-enoate
InChIKey
DMQYPVOQAARSNF-UHFFFAOYSA-N

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted; limited specific CIR review

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for PPG-3 Glyceryl Ether Triacrylate.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for PPG-3 Glyceryl Ether Triacrylate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =150 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID
NOAEL =375 mg/kg bw/day oral Rat reproduction developmental ToxValDB_ECHA_IUCLID
NOAEL =750 mg/kg bw/day oral Rat developmental ToxValDB_ECHA_IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Film former

Expert Verdict

Expert safety assessment and concern-level summary for PPG-3 Glyceryl Ether Triacrylate.

Regulatory Flags

potential-allergen

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to PPG-3 Glyceryl Ether Triacrylate by CAS number or substance name.

Studies
3
Lowest NOAEL
150 mg/kg bw/day
Highest NOAEL
750 mg/kg bw/day
ToxValDB_ECHA_IUCLID

Chemical Function

Film former

Australian Status

AICIS status: listed

Frequently Asked Questions

Is PPG-3 Glyceryl Ether Triacrylate safe in cosmetics?

PPG-3 Glyceryl Ether Triacrylate has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted. 3 toxicological study endpoint(s) are available in our database.

Is PPG-3 Glyceryl Ether Triacrylate allowed in the EU?

PPG-3 Glyceryl Ether Triacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does PPG-3 Glyceryl Ether Triacrylate do in cosmetics?

PPG-3 Glyceryl Ether Triacrylate functions as: Film forming. It is classified as a cosmetic ingredient in our database. CAS number: 52408-84-1.

What is the NOAEL for PPG-3 Glyceryl Ether Triacrylate?

The NOAEL (No Observed Adverse Effect Level) for PPG-3 Glyceryl Ether Triacrylate is =150 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. A total of 3 study endpoints are available. Source: ToxValDB_ECHA_IUCLID.

Is PPG-3 Glyceryl Ether Triacrylate used outside cosmetics?

PPG-3 Glyceryl Ether Triacrylate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Is PPG-3 Glyceryl Ether Triacrylate in Your Products?

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