Excellent Cosmetic Ingredient GHS Classified

Potassium Sulfate

Also known as: Sulfuric acid dipotassium salt, Caswell No. 702, EINECS 231-915-5, EINECS 233-558-0, EPA Pesticide Chemical Code 005603 (+3 more)

INCI: POTASSIUM SULFATE

Potassium Sulfate (CAS 7778-80-5) is a cosmetic cosmetic ingredient functioning as Viscosity controlling. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 7778-80-5 →

Auto-generated CPSR Part A draft with source citations
Function
Viscosity controlling
Safety Rating
EXCELLENT

Chemistry & Identifiers

Formula
K2O4S
MW
174.26 g/mol
EC Number
231-915-5
PubChem CID
24507
IUPAC Name
dipotassium;sulfate
InChIKey
OTYBMLCTZGSZBG-UHFFFAOYSA-L

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes GRAS as food substance; permitted in cosmetics without restriction

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Potassium Sulfate.

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
The substance is mildly irritating to the eyes, skin and respiratory tract.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
1,000,000 - 10,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

PubChem Annotations

Safety and regulatory annotations from PubChem (NCBI) aggregated sources.

Safety (1)
ICSC Safety Card
1451
Source: ILO-WHO International Chemical Safety Cards (ICSCs)
Regulatory (2)
JECFA Evaluation
POTASSIUM SULFATE | 1985 | NOT SPECIFIED | TRS 733-JECFA 29/26 | NOT PREPARED
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
EU Food Improvement
Food additives
Source: EU Food Improvement Agents

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Crystal growth modifiers (nucleating agents) Flavouring and nutrient Processing aids not otherwise specified Thickening agent Viscosity modifier
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Potassium Sulfate.

Regulatory Flags

epa_safer_alternative fda_food_additive jecfa_safe

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Potassium Sulfate by CAS number or substance name.

Studies
12
Lowest NOAEL
256 mg/kg bw/day
Highest NOAEL
1975 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip

Known Synonyms

Sulfuric acid dipotassium salt Caswell No. 702 EINECS 231-915-5 EINECS 233-558-0 EPA Pesticide Chemical Code 005603 Kalium sulphuricum UNII-1K573LC5TV K2SO4

Chemical Function

Viscosity modifier Thickening agent Crystal growth modifiers (nucleating agents) Processing aids not otherwise specified Flavouring and nutrient

Regulatory Lists

inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides pharmaceutical food_additive; Substances Added to Food (formerly EAFUS) (2/2019) SCIL (9/2019) Canada; pharmaceutical Canada; pharmaceutical pharmaceutical inert_ingredient; Pesticides

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
POTASSIUM SULFATE
ChEMBL ID
CHEMBL2021424
Max Phase
4
Adverse Event Associations
24
View full pharmaceutical profile →

Frequently Asked Questions

Is Potassium Sulfate safe in cosmetics?

Potassium Sulfate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Potassium Sulfate allowed in the EU?

Potassium Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Potassium Sulfate do in cosmetics?

Potassium Sulfate functions as: Viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: 7778-80-5.

Is Potassium Sulfate used outside cosmetics?

Potassium Sulfate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Does Potassium Sulfate have different safety status in cosmetics vs industrial chemicals?

Potassium Sulfate is classified GHS Danger (H318) in the chemicals database but is allowed in EU cosmetics.

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